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Re: Zyprexa and MAOIs?

Posted by OldSchool on January 25, 2002, at 15:48:26

In reply to Re: Zyprexa and MAOIs? » OldSchool, posted by ray on January 25, 2002, at 14:29:48

> I've pondered Parnate + Zyperexa in past.
> Was based on 1 day trial of 2mg zyprexa add in (dr. gave me samples), maybe about 2 years ago.
>
> 1)Added 2mg to Nardil 60 + Klonopin.
> 2)As expected got sedated.
> 3)Added 150 Wellbutrin.
> 4)Incredible. Dramatic effect rest of day.
>
> Never thought more because too many meds but learned something.
>
> Currently trying low dose amisulpride.
> Very interesting reminds me of zyperexa experience.
> However not quite right with my regimen.
> Cannot tolerate except very low dose (< 10mg/day!)
>
> Eldepryl makes sense. Decreases prolactin to counter amisulpride increase.
> Eldepryl even low dose blocks sedation from tramadol for example, wheareas Nardil will not at 60mg, it will lead to increasing sedation and with enough tramadol serotonin syndrome (VERY BAD NEWS). (NOTE: NOT MAOI SCARE TACTIC, TRAMADOL + MANY ANTIDEPRESSANTS CAN LEAD TO SEROTONIN SYNDROME).
> Anyway point being Eldepryl even low dose (perhaps even moreso than at higher dose), generally offsets anti-dopaminergic effect of anti-DA meds.
>
> Parnate inbetween Nardil and Elderpyl might go well with Zyprexa at very low dose.
>
> Ray
>

Hi Ray, just watch out for those nasty movement disorders. Once you get one its hard to get rid of and it aint no fun.

Old School


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