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Re: Desipramine and pain » CalvaryHill

Posted by BarbaraCat on January 9, 2002, at 13:13:48

In reply to Desipramine and pain » BarbaraCat, posted by CalvaryHill on January 9, 2002, at 1:26:20

Thank you for taking the time to respond - I am touched and grateful. I am actually going to slowly wean myself off all pharmaceutical medications over the next few months, with massive nutritional, emotional and spiritual support. I have the time to do this and will approach it in an intelligent manner with the support of good friends and husband.

My emotional lability concerns me as well, as I have not been thinking clearly and am easily pulled into dark and terrifying places from which escape is difficult, and extremely wearing to my body and soul. I think the crapshoot of wrong meds have been toxic to my system and I want to clean out. Perhaps I'll reach a steady state and won't require meds for at least a breather period, perhaps I'll learn invaluable lessons in the process, perhaps I'll have to return to biochemical help. My intention is to at least clear out the chemical burdens that are exacerbating an increasingly delicate state of physical health. Your meds suggestion will be what I insist upon from my pdoc as it makes sense. Will keep you all posted as to my progress -- I know coming off of over 20 years of Russion roulette dosing will be no walk in the park, and so ask for your good wishes/prayers, as you all indeed have mine.

> Nortriptyline (a metabolite of amitriptyline) is a better drug overall for the prophylaxis of pain _and_ for anxiety--this is supported by the Psychopharmacology Tips. And nortriptyline has a benign side-effect profile that is comparable to desipramine.
>
> Once you complete a trial with a TCA then the fatigue should dissipate because of norepinephrine dominance.
>
> Your emotional lability concerns me, and your mood-stabilizer dose of Lithium is severely inadequate. I would suggest a trial with Divalproex to smooth out the cycles and also add an antidepressant effect.
>
> Take Care,
> CalvaryHill


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poster:BarbaraCat thread:89346
URL: http://www.dr-bob.org/babble/20020103/msgs/89448.html