Posted by Elizabeth on December 28, 2001, at 14:18:48
In reply to Re: Status of the Selegiline Patch?, posted by OldSchool on December 21, 2001, at 21:05:19
Food interactions are not a concern with parenterally administered MAOIs (because the MAOI avoids passing through the GI tract), but there are still risks from drug-drug interactions (with SSRIs, decongestants, certain opioids (Demerol, Ultram), etc.).
The FDA frequently drags its feet approving new drugs. I'm still wondering if sublingual buprenorphine is ever going to be available in the U.S.
Until the patch is approved (if it ever is!), you always have the option of taking high doses of oral selegiline (you must observe dietary restrictions if you're going to do this, but as I've often said, the MAOI diet isn't really that big a deal -- I've posted the list of restricted foods here several times, and you could probably find it by searching the PB archives). Selegiline is often tolerated by people who have trouble with other MAOIs; it seems to cause fewer problems with weight gain, cardiovascular effects (hypertension and orthostatic hypotension), etc. than other MAOIs often do. Personally, I found it jittery, but then again, I was already having some pretty problems with untreated anxiety at the time.
-elizabeth
poster:Elizabeth
thread:87632
URL: http://www.dr-bob.org/babble/20011222/msgs/88053.html