Posted by OldSchool on December 22, 2001, at 12:55:40
In reply to Write to the FDA?, posted by spike4848 on December 22, 2001, at 12:05:01
> It seems the patch has helped so many people ... often when no other treatment works. In other diseases like HIV and cancer, medication gets fast track approval by FDA. Well, depression is a life threatening disease also. Maybe we all should collectively write FDA to speed up the patch's approval process!
>
> All in favor, say "I."Well the thing about this MAOI patch is Ive read the FDA lifted the requirement for the MAOI diet in later stage trials. I read that Dr. Bodkin said when the Selegiline goes right into the bloodstream bypassing the gut, this eliminates the need for the MAOI diet. If this is true, that would be fantastic for some of us who would very badly like to try an old style MAOI for refractory depression. But cannot deal with the MAOI diet, nor the potential for a hypertensive crisis.
So to me, from the things Ive read, the Selegiline MAOI patch seems like you can have your cake and eat it too. You get the MAOI antidepressant effect which is second to none, but you dont have to go on the MAOI diet and need not worry about blood pressure problems.
Of course, if it turns out you still must adhere to the MAOI diet on the patch, I dont even see the point in going thru all the trouble of developing the MAOI patch. To me, thats the whole advantage of it.
here is an article about the MAOI patch, in which its mentioned the FDA lifted the MAOI diet restrictions on later stage trials.
http://www.news.harvard.edu/gazette/1998/12.10/depression.html
I could use an MAOI right NOW, however I cant hang with this pain in the ass MAOI diet, nor can I risk blood pressure/stroke problems. Frankly I could use this MAOI patch NOW, not a year or two from now.
Tell the FDA to hurry up, there are many many refractory depressives who would like to try MAOIs but dont want to take the pill form because the MAOI diet is incompatible with a good lifestyle (I like to eat).
Old School
poster:OldSchool
thread:87632
URL: http://www.dr-bob.org/babble/20011222/msgs/87692.html