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Re: Post Traumatic Stress Disorder and etc.

Posted by JGalt on October 27, 2001, at 13:14:50

In reply to Re: Looking for some advice before I see the psydoc » JGalt, posted by JohnX2 on October 27, 2001, at 1:15:47

Post Traumatic Stress Disorder, your brief discussion on it will probably lead me to research it some later. I have heard it before in reference to police brutality, but never anywhere else. So basically it can apply to any situation that your body stays in the fight-flight response much longer than it should and no amount of "thinking yourself down" from the event will help. I've had that a lot at times, in fact, I believe part of my problem is that when I need to get something done, I not only have some lack of motivation do it, there's also a certain fear response that my body produces. Like fear of getting started and then fear of continuing. I don't know why, I succeed at most things I try at, but I never even thought about it until reading your post, that that, in combination with low energy, is why I have trouble setting out on projects that would probably provide me with pleasure, and perhaps increased energy. At times this feeling of fear can also lead me to decide to not do something I know I should do that would help to ensure the success of something I'm trying at.

Adderal, the 6 total times I've tried it, helps wonderfully, but even though I never have taken it on consecutive days, the next day I will always be low on energy and motivation, which is why I know it is addictive and has a high tolerance building potential. But Adderal, in addition to providing me with motivation, seems to completely eliminate this, whatever the heck it is.

GHB (or things that convert to GHB) is the only other drug that does so, but of course it also has some negative things about it too. While it does NOT produce tolerance, if you have ever used it several weeks in a row without break, and to help get to sleep at times too (resulting in no REM sleep), you know its effects on memory and causing ADD like behavior...it does need to be stopped every once in a while or else you will have trouble focusing on tasks, and short+long term memory will be reduced, and connections between things in your mind are reduced too. This is of course if you abuse it, which I now know where the line between abuse and use is. It produces a feeling of love+trust towards everything, which can sometimes be a negative aspect. Enough about that, the fact is, it, and Adderal, both are able to eliminate this fear of doing, though adderal obviously has many more positive things about it until you develop complete tolerance. Still, GHB is a very theraputic chemical (it is present in your body and food too) when used properly, and its lack of tolerance is very nice.

Still, Selegiline does not eliminate this problem really, it simply provides some more motivation to do things, and also is stimulating. This allows one to use GHB effectively, as it helps to keep one more alert while on it, and reduces the effective dosage quite nicely.

Well after all that ranting, can you give me any insight or advice into my problem? Since you mentioned the NMDA antagonists being helpful in this regard, I think I may eventually try a combination of lamictal+adderal. I would think that if lamictal reduces NMDA receptor sensitivity, that it would work roughly the same, do you think I am correct?

I personally would love to try my idea mentioned before of adderal+low dose dxm+prozac+1,4 butanediol (GHB precursor), but I know that no psych doctor is going to go for a such a combination. Of course, then again, if I were to do such a combination, I would obviously not mention the rationale behind it or either of the two non-mainstream chemicals.

Your approach seems like a logical one to the problem. I cannot understand why someone would not research a drug or drug combination that some person had given them or the disease for which they are taking it. Even GHB can't make me that trusting!

I can understand why wild euphoria is not what you're looking for. One should desire their emotional state to have connection with real life events. Having wild euphoria while washing off an apple would not be particularly pleasurable because one knows that one's pleasure is not stemming from what one is doing. That is why I would question a drug that kept a person very happy all the time, or a person who would want to be. While I would certainly have no qualms about a majority of the people being on a drug that increased the capacity of their pleasure, or perhaps simply multiplied all positive emotions by 2 and divided all negative emotions by 2, I would have a problem with a drug that made all emotions more positive by a factor of 2 being used for anyone that wasn't truly depressed.

I see what you mean about true mania being induced by caffeine having the potential to damage dopamine receptors.

Also interesting that my thoughts about gaba agonists working to protect from NMDA hypoactivity have already been proven. I'll have to do some research to find out just what the gaba agonists are, and whether ghb or precursors are amongst them. If that is unknown, perhaps I'll also have to find out if drugs which are specific gaba antagonists exist outside of a chemical lab, evaluate their safety, and see if they prevent GHB's effects. This could take a while, but it might pay off. Sometimes I wonder why the same people that prescribe the drugs aren't the ones that go through pharmacy school to learn how drugs work and how to make interesting combinations of them.

JGalt


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