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Re: sulpiride, d2 antagonist?

Posted by JahL on October 21, 2001, at 17:11:54

In reply to Re: sulpiride, d2 antagonist? » JahL, posted by kregpark@yahoo.com on October 21, 2001, at 15:12:13

> Just did a quick look but looks like maybe sulpiride is d2 antagonist primarily.

I could've sworn my pdoc said it was preferential for D3. Then again he said there was no possibility of TD, something the rsch papers don't seem to bear out. You know that Amisulp & Sulp work differently @ low doses, working as pre-synaptic antagonists?

> Maybe is more sedating than amisulpiride at low dose?

I have no problems with sedation @ 100mg. Sedation starts to set in around the 200mg mark but this higher dose yields no further benefits anyway. Funnily enough it was Amisulp that left me feeling groggy.

J.


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