Posted by Elizabeth on September 14, 2001, at 8:24:57
In reply to Re: DXM in Ecstasy, posted by stjames on September 13, 2001, at 15:25:25
> > Okay, I looked into this. Codeine, morphine, hydrocodone, oxycodone, hydromorphone, oxymorphone, buprenorphine, diamorphine, and fentanyl don't have any serious interactions with MAOIs. Butorphanol, propoxyphene, and methadone might. Ultram and Demerol definitely do. Not sure about pentazocine and nalbuphine.
>
> James here....
>
> SS happens to 5HT effecting AD's, not just MAOI's.But MAOIs are the highest-risk drugs. If something doesn't cause the CSS with MAOIs, it's a good bet that it won't cause it with SSRIs or other serotonergic ADs, either.
I think the oxycodone thing was an idiosyncratic response. The case you cited is the only one in the literature, and it was in a bone marrow transplant patient so there could easily have been other factors involved. There's no objective test for CSS, and other conditions can mimic it.
BTW, it's "DXM," not "DMX." Isn't DMX the name of a band or something? :-)
-elizabeth
poster:Elizabeth
thread:78291
URL: http://www.dr-bob.org/babble/20010907/msgs/78749.html