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Re: Effexor and Dieting » Maisy

Posted by SalArmy4me on August 23, 2001, at 6:50:06

In reply to Effexor and Dieting, posted by Maisy on August 23, 2001, at 6:22:23

Here is something to consider as far as psychopharmacological treatment of Effexor side-effects:

Journal of Clinical Psychopharmacology
Volume 20(6) December 2000 pp 716-717
"Orlistat in the Treatment of Psychopharmacologically Induced Weight Gain
[Letters to the Editors]"

"Discussion
These are the first reports of orlistat administration in obese patients receiving psychopharmacologic medication with psychiatric axis I comorbidity. This medication was very well tolerated by both patients. Although the patient in the first case was prone to obesity before medication, her body weight increased significantly during amitriptyline and lithium treatment (on admission, grade 1 obesity; after 2 years as an outpatient, grade 2); in the second case, the patient also showed a substantial weight gain and even new obesity occurred (grade 0 on admission, grade 1 after 2.5 years). In both patients there seemed to be a relationship to the psychotropic medication that could not be easily changed because of the course and severity of the underlying psychiatric disorder. Orlistat had the advantage not to be centrally active, so it did not interfere with the psychiatric disorder as one might have expected in the case of the new serotonin-noradrenaline reuptake inhibitor and appetite-suppressive drug sibutramine.9 Nevertheless, orlistat led only to a mild additional decrease in weight, but it was comparable to that achieved in former studies in patients without psychiatric disorders.10 In summary, orlistat might be a tool to help control weight in selected patients with psychotropic drug-associated obesity."

Ion Anghelescu, MD


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poster:SalArmy4me thread:76085
URL: http://www.dr-bob.org/babble/20010822/msgs/76086.html