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Re: Serotonin vs. Dopamine Deficiency - Symptoms?

Posted by ChrisK on August 16, 2001, at 3:39:35

In reply to Re: Serotonin vs. Dopamine Deficiency - Symptoms?, posted by JohnL on August 15, 2001, at 18:07:10

I agree with John from an anecdotal standpoint. My anhedonia/apathy only lifted with the addition of Mirapex which is a Dopamine agonist. SSRI's never did a thing for me. I guess that it's true that everyone's depression and reaction to meds is unique.


> > > Has anyone come across either an article in Medline or a Web page that compares the symptoms that are associated with a deficiency of serotonin vs. the symptoms that are associated with a deficiency of dopamine?
> >
> > I'd really like to know the answer to this question. Web address anyone?
>
> I too would like to see some research on this topic. I think the entire psychiatric community is missing the boat by not focusing on exactly what you are asking about.
>
> From my own anecdotal experience, I think dopamine deficiency is more related to symptoms of blahness, lack of pleasure, anhedonia, dysthymia. Dopamine deficiency is not really like being depressed, but it's more like just being blah, lifeless, and nothing at all is enjoyable. You ask a good question. I wish we had some solid answers. But I am firmly convinced that symptoms related to dopamine represent a totally different beast than symptoms related to serotonin, even though nearly all doctors at this point lump them into the same group.
> John


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