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Is Paxil and Efexor together save ?

Posted by ben on August 14, 2001, at 15:21:02

There is a theoretical interaction between Paxil and Efexor: Paroxetine (Paxil) inhibits the enzyme CYP2D6 which is responsible for the metabolism of Venlafaxine (Efexor). Could this drugs be combined "in praxis". I take 40 mg Paxil and have the idea of adding some Efexor. Any experiences or suggestions ?

P.S
I know someone who takes 450 mg Efexor along with 20 mg of Prozac instead there is the same theoretical interaction (Fluoxetine and Norfluoxetine are inhibitors of CYP 2D6 as well as Paroxetine). She didnt developed some strong or dangerous side effects.


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poster:ben thread:75069
URL: http://www.dr-bob.org/babble/20010814/msgs/75069.html