Posted by Elizabeth on July 9, 2001, at 19:16:53
In reply to Re: trazodone, REM sleep, etc., posted by chiaratara on July 9, 2001, at 13:43:08
chiaratara:
> try trazadone. it is supposed to help with sleep architecture. good luckWhether it "helps" with sleep architecture or not depends on what your problem is. It's a pretty strong antihistamine (in a pinch, I once used it for the itchies), and this probably accounts for its sedative actions. It does increase sleep continuity and total sleep time (two of the problems often caused or exacerbated by SSRIs and Effexor) and decreases sleep latency (the amount of time it takes to get to sleep), but those aren't usually what is meant by "sleep architecture." Trazodone decreases deep (stages III-IV) sleep and REM sleep and increases non-REM stages I-II sleep. Like I said, whether or not this is a good thing depends on what your problems are.
Also, trazodone can cause nightmares for some people (probably due to serotonin agonism, particularly by its anxiogenic metabolite meta-chlorophenylpiperidine (mCPP)).
-elizabeth
poster:Elizabeth
thread:65315
URL: http://www.dr-bob.org/babble/20010708/msgs/69516.html