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Re: Remeron - less sedation at higher dose? » Judy

Posted by Elizabeth on July 4, 2001, at 21:36:43

In reply to Re: Remeron - less sedation at higher dose? » Elizabeth, posted by Judy on July 3, 2001, at 18:34:28

> Elizabeth - I know you've tried several of the MAOI's so I hope you'll offer your opinion on this:

My opinion is always available < g >. (I've taken Nardil, Parnate, selegiline, and Marplan.)

I didn't get much benefit out of Remeron, but there might have been confounding factors. I'd like to try it again. A friend who has many of the same type of symptoms as I have, and who has had success with buprenorphine as well, had a good response to Remeron but couldn't deal with the weight gain. His depression and anxiety are at least partially due to an extensive history of heroin addiction, but I think he originally started abusing drugs because he had problems similar to mine and opioids relieved them. He also responded well to Nardil but again didn't want to deal with the weight gain. Anyway, he was very impressed by Remeron. He'd tried a lot of other ADs (SSRIs, etc.) without success.

> The only AD's I've ever responded to were Nardil (best I've ever felt) and, to a lesser degree, Marplan; but I can't tolerate them physically (severe edema, almost total shutdown of my bowels and bladder, etc., etc.)

Bethanechol works for urinary retention; psyllium fiber (e.g., Metamucil) plus docusate (a stool softener) should alleviate constipation. (Having to deal with all this stuff is a pain, I know.) There must be some way to treat the edema too (diuretics maybe?).

> Remeron is the only AD I've never tried and I've been staring at the newly filled script bottle for over a week now, dreading the sedation almost as much as I do my depression/dysthymia/anxiety.

Like I said, I started at 30mg and increased it rapidly to 60 or 75, and I didn't have any problems with sedation (or weight gain, for that matter). I was able to take it at bedtime even at the higher doses.

-elizabeth


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