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Re: One more try - Klonopin and Wellbutrin » Joe Schmoe

Posted by Rick on July 4, 2001, at 4:40:29

In reply to One more try - Klonopin and Wellbutrin, posted by Joe Schmoe on July 3, 2001, at 10:43:11

Believe me, Wellbutrin won't neuter you! It almost never causes sexual dysfuntion. In fact, sometimes it actually enhances sexual function.

But as Else suggested, it definitely has the potential to make you feel wired, especially until you get used to it. I trust your doc is going s-l-o-w working you up to the 300. If you have the opportunity to first try the Klonopin solo for awhile, that would be a good because within a week or less you should have a sense of whether it's working out for your SP (which I fully expect). Of course if you experience pretty severe depression, it may be best to start ramping up on the AD right away.

I actually tried Wellbutrin (100 mg.) with Klonopin and Celexa, before I hit on the cocktail I've used for a year now. The Wellbutrin was added to offset lethargy and apathy brought on by the Celexa. It did indeed help on that count, but it also reversed some of the SP benefit of the Klonopin by making me kind of jittery. That said, if I had ramped up on it real slow, it might not have had the adverse effect. (My pdoc actually suggested starting at 25 mg and moving up slowly...I should have followed his advice. I felt no adverse effect at 50mg, so I made the mistake of jumping up to 100 mg too quick.) And there are definitely anxious people who do well with it once they get used to it, although there should usually be something of a more calming nature in the mix -- in your case, Klonopin. Wellbutrin can cause insomnia in a lot of folks, especially early on, but Klonopin should do a lot to help prevent that -- even if taken during the morning or afternoon.

BTW, you mentioned the size of your Klonopin pills, but not the daily dosage. Does this mean you're taking it as-needed? If so, you *might* find you need it pretty regularly as you adjust to likely activation effects from the Wellbutrin.

Good luck to you. I think you've got a real good chance of doing well with this combo for both your depression and your SP, especially if you start-low-go-slow with the Wellbutrin.

Rick


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