Re: Just how much do the SSRIs inhibit norepinephrine? » SalArmy4me

Posted by Sunnely on July 3, 2001, at 20:22:53

In reply to Just how much do the SSRIs inhibit norepinephrine?, posted by SalArmy4me on July 2, 2001, at 0:01:00

The following is a comparison of concentration (nmol/L) of SSRIs needed to inhibit specific neurotransmitter uptake by half:
1. Serotonin:
Fluoxetine = 6.8; Fluvoxamine = 3.8; Sertraline = 0.19; Paroxetine = 0.29; Citalopram = 1.8
2. Dopamine:
Fluoxetine = 5000; Fluvoxamine = 42000; Sertraline = 48; Paroxetine = 81; Citalopram = 40000
3. Norepinephrine:
Fluoxetine = 370; Fluvoxamine = 620; Sertaline = 160; Paroxetine = 81; Citalopram = 6100

> I heard on a Grand Rounds at Univ. of CA, Los Angeles that paroxetine inhibits norepinephrine 40%. Could that be true? I know that Citalopram has no action on norepinephrine, though.

Thread

Just how much do the SSRIs inhibit norepinephrine? SalArmy4me 7/2/01
Re: Just how much do the SSRIs inhibit norepinephrine? » SalArmy4me Mitch 7/2/01
Re: Just how much do the SSRIs inhibit norepinephrine? » SalArmy4me Cam W. 7/2/01
Re: Just how much do the SSRIs inhibit norepinephrine? » Cam W. Mitch 7/3/01
Re: Just how much do the SSRIs inhibit norepinephrine? » SalArmy4me Sunnely 7/3/01
Re: SSRI's relative contribution to extra DA/NE » Sunnely Mitch 7/4/01

Post a new follow-up

Notify the administrators

Start a new thread

poster:Sunnely thread:68694
URL: http://www.dr-bob.org/babble/20010701/msgs/68886.html

	for
in