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Re: Just how much do the SSRIs inhibit norepinephrine? » SalArmy4me

Posted by Mitch on July 2, 2001, at 12:23:00

In reply to Just how much do the SSRIs inhibit norepinephrine?, posted by SalArmy4me on July 2, 2001, at 0:01:00

Sal, I doubt that. My pdoc showed me a chart that listed all of the SSRI's and all the reuptake pump affinities. From what I remember in order of affinity for NE reuptake pumps Prozac had the most affinity with Luvox/Zoloft in the middle and Celexa/Paxil with the least affinity.
Zoloft had a modest affinity for DA reuptake inhibition and Paxil had a modest affinity for ACH reuptake inhibition.

Mitch

> I heard on a Grand Rounds at Univ. of CA, Los Angeles that paroxetine inhibits norepinephrine 40%. Could that be true? I know that Citalopram has no action on norepinephrine, though.


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