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Re: Studies: New Celexa promising » Rick

Posted by Mitch on June 1, 2001, at 23:26:59

In reply to Re: Studies: New Celexa promising, posted by Rick on May 30, 2001, at 21:16:04

I saw a Medline abstract months ago talking about the pharmacologically active metabolite of nortiptyline (Pamelelor) 10-hydroxy-nortriptyine as having serotonin down-regulation effect and anxiolytic effects. They mentioned that it ought to be pursued as a possible separate med to develop.

> Does anyone know if any other AD's have similarly refined versions in the works? Perhaps Pregabalin and the metabolite of BuSpar (I forget the name) fall into this category, although they are anti-anxiety meds. Also, about a year ago, I read about testing on a new version of Valium without the side effects and dependence or addiction risks.
>
> (Sorry if any of this has already been discussed. I haven't visited P-B a lot lately, and I wouldn't know what search terms to enter to find relevant posts.)


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URL: http://www.dr-bob.org/babble/20010530/msgs/65127.html