Posted by NikkiT2 on May 13, 2001, at 16:18:30
In reply to Tamoxifen - experience with as a mood stabilizer?, posted by Chris A. on May 10, 2001, at 12:39:46
I am so interested and waiting for thisd to hit the UK. There is a strong hsitory of breast cancer in my family, and my mum was on this for a number of years.
I'd love to know if it helps.
nikki
> My consultant recommended Tamoxifen as a mood stabilizer. It is the estrogen
> antagonist prominent in breast cancer treatment. I haven't started it, as I have been
> taking high dose estrogen for it's much touted neuro-protective effects. He says the
> evidence that estrogen is neuro-protective is very weak and has been over publicized.
> At 48 I have just gone off of my estrogen to see where I'm at, and as a possible
> intermediate step towards Tamoxifen. In reading Dr. Manji's research results, I'm
> feeling that this is a tentative treatment with a lot of risks. It's supposed to be a PKC
> inhibitor like depakote and lithium. It is also aimed at refractory mania. Since my
> experience is 95% depressive in nature I am concerned that it might leave me flattened
> out at the bottom at best, like Nimodipione did. I am diagnosed mixed bipolar and the
> only mood stabilizer that I've tolerated is Lamictal. Ziprasidone caused really bad
> akithisia, so I don't want to go back on it with a beta blocker (another pill to take and
> opay for, not to mention dealing with more side effects - aaarrrgghh!) It would be nice
> not to be so internally restless that I can't sit through my daughter's graduation. At least
> there is another milestone that it is important to stay alive for. If it weren't for milestones
> I wouldn't have survived thus far.
>
> If anyone has had experience with Tamoxifen I would like to hear about your
> experience.
>
> Thanks in advance,
>
> Chris A.
poster:NikkiT2
thread:62381
URL: http://www.dr-bob.org/babble/20010507/msgs/62774.html