Posted by KS on May 1, 2001, at 12:32:05
I would really like to know if anyone suffers the same exasperating problem that I do. My doctors haven’t given me a name for it – so if you have the name, please hand it over! I’ll have to give you the long story in the absence of short-cut jargon to describe my condition. I am “immune” (poetic licence) to benzodiazepines, phenothiazines and some anesthetics. This is a problem as I am insomnia, generally anxious and have good old “treatment resistant depression”. For example, I could take about 6mg of Klonopin (clonazepam) and it would –at best – have a very mild anxiolytic effect that would last about an hour. I’ve tried large doses of Rohypnol (flunitrazepam) but even 8mg allowed me to happily socialize and watch the late night movie! With antidepressants that are supposed to have sedative side-effects, I feel absolutely nothing. Also, any antidepressants I have tried (and there have been many) have always had to be taken to maximum dose before they had a mild effect on me. My GP was shocked when she gave me 2 injections of Stemetil (antiemetic phenothiazine) and a double dose of Pethidine the other day. She thought she’d have to call my wife to cart me away but, since it was the last appointment of her day, I merrily chatted to her for half an hour or so before driving home! Does anyone else have this problem? I think it might be genetic as my mother has the same “immunity”? I would appreciate any feed back, specially about how to overcome it. Some have suggested it a metabolism problem?
Look forward to hearing from you.
KS
poster:KS
thread:61258
URL: http://www.dr-bob.org/babble/20010424/msgs/61258.html