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Re: If Zyprexa BLOCKS dopamine, what good is it?

Posted by loosmrbls on March 29, 2001, at 12:13:42

In reply to Re: If Zyprexa BLOCKS dopamine, what good is it?, posted by Eric on March 29, 2001, at 9:05:33

I believe all the antipsychotics block dopamine by acting as receptor antagonists -- that is, they don't lower the amount of dopamine, but they "jam up" the receptors so that the extra dopamine can't bind to it's receptors and cause an effect. I'm not sure about the low-dose causing an increase in dopamine.

Zyprexa was approved to be used in acute mania and short-term mood stabilization, but not as maintenance therapy like lithium or depakote.


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URL: http://www.dr-bob.org/babble/20010327/msgs/57943.html