Posted by MarkinBoston on February 16, 2001, at 0:22:27
In reply to Re: Targeting cortisol for depression? Mark, posted by JasonL on February 15, 2001, at 18:27:11
I'm taking 225-300mg/day of non-XR Effexor and 20-40 mg of Adderall/day. I think my AM cortisol was about 18 or 19 and estradiol 50. Besides cortisol, testosterone and estradiol share the same diurnal profile. Ketoconazole will wipe them all out and should have you feeling less miserable and functional enough to get on another AD. Previously, I have tried Nortryptaline with Effexor. The side effects were not too bad, but I stopped taking it because it didn't seem to add to what Effexor was doing.
Did you do a Dexamethasone suppression test? The wierd thing is that I felt fantastic the day after taking 1 mg. Anyone else? Dex isn't a long term option, unfortunately.
> Mark,
>
> Thanks for your insight. I think I will try the ketoconozole when it arrives. I have to check around, but I think ketoconozole inhipits the p450 enzyme which Paxil also does too. This could be a problem. I have yet to find an anti-depressent to pull me out of a severe depression that has lasted for years.
>
> What AD is helping you right now?
>
> JasonL
poster:MarkinBoston
thread:53836
URL: http://www.dr-bob.org/babble/20010212/msgs/54124.html