Posted by Rzip on February 14, 2001, at 19:19:41
In reply to Re: Bad to cut Zyprexa in half?, posted by Lorraine on February 14, 2001, at 18:57:41
> Lin: This is from the tips board:
>
> Date: Mon, 14 Oct 1996 17:27:27 -0500
> From: Lauren Marangell MD < laurenm@bcm.tmc.edu >
> Subject: Cutting olanzapine tablets
>
>
> I was informed by my drug rep that Zyprexa (olanzapine) tablets should not be cut because of potential O2 degradation and that crushing is strictly verboten because it is potentially volatile!
> --Mary D. Moller
>
>
>
> --------------------------------------------------------------------------------
>
> Date: Mon, 9 Dec 1996 02:21:13 -0800
> From: Tina < tinam@tidepool.com >
> Subject: Cutting olanzapine tablets
>
> I was told by our Lilly rep that you should not cut olanzapine tablets, that the coating on the tablets is there to protect the very light sensitive compound inside. The "leftover" half of the pill turns brown quickly (though the clinical significance of this was not explained).
>
> If you do split tablets, you are supposed to discard the portion you are not using, so the cost factor stays the same.
poster:Rzip
thread:54003
URL: http://www.dr-bob.org/babble/20010212/msgs/54020.html