Posted by michael on November 30, 2000, at 19:20:39
In reply to Re: AmisUlPiRiDe: to andrew, johnl L or anyone, posted by JohnL on November 30, 2000, at 4:33:16
Hey John,
Just for the record, I think I may have been the one you're thinking of who reported sedation w/amisulpride. It was pretty significant - slept at least 12 - 15 hours a day. Totally disappointed me.
However, that was a week after I had stopped a trial of prozac, and I think that's significant. I think the interaction or combination of the two is what did me in (the long half-life of prozac...)
I say this because I'm trying it again, (w/o any prozac) and not having that type of response... It's only been a week or so, but last time, I only tried it for a week, because the sedation was so significant, and set in immediately.
This time I'm trying it in addition to the adrafinil I've been using (ever hear of that idea anywhere?). It may be a bit early to tell, but I think I may getting the kind of response I have read about, and had been hoping for the first time I tried it. (addressing anhedonia/fatigue issues).
Anyway, glad to hear things are going well for you, and just wanted to clarify why I think I had that reaction to the amisulpride on that occasion. Keeping my fingers crossed...
michael
> Howdy,
> It's no secret I'm a big fan of Amisulpride and Adrafinil. So I would strongly agree they are worth a try.
>
> Adrafinil is unique in that it even works with normal people. Some of the expected effects are: passive people become more active, quiet people become more talkative, shy people become more outgoing. These would all seem encouraging if trying to treat social anxiety.
>
> Amisulpride alone can have the same effects, though it's a little different flavor. Hard to explain. And even though both are usually on the slightly-stimulating side rather than sedating, they also can also reduce anxiety simultaneously. Of course there are exceptions, but that is generally what I've experienced and generally what I've heard from others. I have always been shy and reserved, but with these drugs I find myself comfortable in a crowd and comfortable talking to anyone in any situation.
>
> I have heard of one person who was not helped by these drugs. Another got sedated on Amisulpride. Another got anxiety from Amisulpride. So there are exceptions. But usually I think you can expect good things to happen if you are trying to treat social anxiety. As I've often stated, I think Amisulpride+Adrafinil together are far better than either alone. For me a mere 33mg Amisulpride + 300mg Adrafinil works well. Expect anywhere from one day to three weeks to experience good changes in your symptoms. I've noticed other people usually take higher doses than I do, so that's certainly worth trying if low doses aren't enough. Either or both of these drugs stand an excellent chance of wiping out those blah numb feelings you are having, while at the same time improving your core symptoms. Definitely worth a try as I see it.
>
> You may be able to reduce doses of Effexor and Xanax too. But, one thing at a time to avoid confusing results is usually a good idea. Admittedly I don't always follow this good idea myself. Sometimes I screw things all up and have no idea which drug did what, sometimes I get lucky. With Amisulpride+Adrafinil, and a small dose SSRI(Prozac) in the backgound, I got lucky.
> John
poster:michael
thread:49646
URL: http://www.dr-bob.org/babble/20001130/msgs/49717.html