Posted by R.Anne on November 22, 2000, at 19:33:23
In reply to Any one have a theory?, posted by Sherry on November 15, 2000, at 17:30:15
Dear Scott,
I was going to ignore something but I want you to know that I did not appreciate your statement in here that I have marked with three asterisks. I don't like to be referred to that way.r.anne* SSRI-induced weight-gain is poorly understood. Weight-gain produced by SSRIs is considered to be a paradoxical
reaction. That this paradoxical reaction is so frequently seen on Psycho-Babble may be an indicator of a bias
towards an array of serotonergic (5-HT) dysregulations that is overrepresented in a population biased towards
treatment-resistance and "poop-out".Serotonergic systemic and synaptic relationships are very complex and, in my way of thinking, vulnerable to a
broader set of potential dysregulations.In addition, despite their claimed selectivity, SSRIs still interact with various other important systems. The term
"selective" was originally chosen to describe the tendency of these drugs to interact more exclusively relative to the
three major monoamine neurotransmitters recognized as being important at the time (dopamine, norepinephrine, and
serotonin). It is a misconception to think of SSRIs as being selective with respect to all other neurotransmitters and
neuromodulatory systems.*** In other words, most of you Babblers are just plain f_cked-up.
The SSRIs is obviously the class of drug in the greatest demand for an understanding as to why they cause
weight-gain. I apologize for not being able to more precisely report the mechanisms underlying this "unappetizing"
side-effect.
poster:R.Anne
thread:48867
URL: http://www.dr-bob.org/babble/20001115/msgs/49263.html