Posted by SLS on September 30, 2000, at 13:04:50
In reply to Re: Stopping and Restarting MAOI----SLS, posted by stephanie l. on September 30, 2000, at 10:31:16
Dear Stephanie,
If the only thing that stands in the way of your trying reboxetine is that you have no source, I can provide information as to a reputable and reasonably priced pharmacy in London, England. If your doctor is willing to use it right now knowing that you are obtaining it from a foreign source, please email me. I had a bad reaction with reboxetine. It made my depression worse, produced anxiety, and provoked thoughts of suicide. This, of course, is a risk of all antidepressants, so I would make a decision based on just one account. But it can happen. I know of two other people for whom reboxetine exacerbated their depression. However, it seems that reboxetine, a SNRI (selective norepinephrine reuptake inhibitor), may be generally more effective than the SSRIs (selective serotonin reuptake inhibitor). I would DEFINITELY try it if I were you. Both yohimbine and reboxetine work on norepinephrine. That yohimbine helps you may be a good indication that reboxetine will hit the target and chase away the beast.
Now for the tricky stuff. It is my speculative opinion that it is most likely safe to combine reboxetine with the Nardil you are currently taking. If I had not had such a bad reaction to reboxetine, my doctor was prepared to add Nardil. Yohimbine is another story. I would urge you to discontinue yohimbine before you begin reboxetine. There is no two-week "wash-out" period, so you can probably begin reboxetine a few days after your last dose of yohimbine. You can try to add it back later if you feel you need it. I know that Vivactil is a potent norepinephrine reuptake inhibitor, but reboxetine is different enough that I would not guarantee that it will mix as safely with yohimbine as does Vivactil. It is most likely that you did not tolerate "normal" dosages of yohimbine PRECISELY because it was potentiated (exaggerated) by Vivactil.
Have you ever tried desipramine (Norpramin)? Desipramine is definitely a SNRI.
- Scott
poster:SLS
thread:43904
URL: http://www.dr-bob.org/babble/20000926/msgs/45525.html