Posted by Sunnely on August 5, 2000, at 16:12:36
In reply to Re: Update on SAM-e. Really works. Prices coming down., posted by michael on August 5, 2000, at 12:36:18
> Just wondering if those of you that have had some success with sam-e have also been taking the vitamins noted below (B12 & folic acid)? Are they critical to the effectiveness of sam-e? Or have some of you also had success w/sam-e while not taking the additional vitamins?
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> And just dbl checking - is that 1000mg or 1000mcg of B12? Just wondering because the multivitamins I just looked at on my shelf only has 6mcg of B12... Thanks. michaelSAM-e (pronounced "Sammy") was discovered and isolated in 1952. In the early 1970s, a formula for the preparation of a stable salt of SAM-e was patented. SAM-e stands for S-adenosyl-methionine. It first became available in the U.S. in March, 1999.
OTHER THINGS YOU SHOULD KNOW ABOUT SAM-e:
1] Use only an enteric-coated product, because SAM-e is thought to be absorbed more efficiently in the intestines than in the stomach.
2] SAM-e is not well-absorbed in the presence of food, so patients should take it in between meals.
3] Folate (folic acid) and vitamin B12 are necessary for the proper utilization of SAM-e. Taking supplements containing 800 to 1000 mcg (microgram) or 0.8 to 1 mg (milligram) of folate and 500 mg of B12 per day should be more than enough.
4] Dosing is highly variable. While some respond to 200 mg/day of SAM-e, others do not respond to less than 800 mg twice daily.
5] Keep in mind that SAM-e, like all antidepressants, can induce mania.
poster:Sunnely
thread:41637
URL: http://www.dr-bob.org/babble/20000729/msgs/42240.html