Posted by Johnturner77 on June 29, 2000, at 8:56:54
In reply to Re: sulpiride/Michael, posted by Anna P. on June 28, 2000, at 15:11:03
> > I´m taking sulpiride with excellent results, but I´ve read it could induce extrapyramidal symptons in 30% of uusers, even parkinsonism and tardive diskinesia, as other neuroleptics. Is that true? Is amisulpride better in this sense? Can anybody help me?
>
I don't believe extrapyramidal effects are an issue at AD doses. I am not as familiar with Sulpride, but Amisulpride is a neuroleptic at high doses and an AD at low doses. This is because it preferentially blocks dopamine at presynaptic sites. So at low doses it actually increases dopaminergic activity. I beleve Sulpride acts in a similar way. Therefore, at low doses, it might actually work to prevent extrapyramidal symptoms. I hope someone will correct me if this isn't correct.
poster:Johnturner77
thread:31704
URL: http://www.dr-bob.org/babble/20000619/msgs/38688.html