Posted by PeterJ on May 15, 2000, at 1:27:33
In reply to Amineptine substitute? Peter J, Scott, posted by AndrewB on May 14, 2000, at 8:58:08
> I would like to find an acceptable substitute for amineptine. It is a dopamine reuptake inhibitor. It seems like the only other D uptake inhibitors out there are cocaine and Mazindol. Is amineptine a somewhat stepped down version of cocaine that allows at low doses a mild long term psycho stimulation without rebound fatigue or withdrawal? Mazindol seems to be unacceptable. One report said that it caused significant anxiety and did not improve activity level.
>
> There are a lot of amphetamine analogues and precursors out there. One called fencamfamine is listed as an antidepressant. Maybe something like this or even adderall would substitute somewhat for amineptine. Any ideas? Do all amphetamines type drugs cause tolerance and rebound effects?While there is no precise substitute for amineptine, amphetamine (e.g. Adderall) might be close. Ritalin is another option.
Tolerance and dependance are a potential problem with all amphetemine-like drugs. The individual response is variable. Some people respond to the same dosage for years, while others develop rapid tolerance. (I know of no way to predict responses, except one's previous response to simulants.)
Some psychiatrists have suggested that co-treatment with an antidepressant and a stimulant may produce a more lasting effect. A combination of desipramine with amphetamine or ritalin would be an example.
L-Deprenyl is also worth consideration for long term DA enhancement.
Peter
poster:PeterJ
thread:33419
URL: http://www.dr-bob.org/babble/20000508/msgs/33459.html