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AndrewB--TMG dosing question?

Posted by Abby on May 5, 2000, at 17:44:40

In reply to Re: TMG??, posted by AndrewB on April 29, 2000, at 21:32:53

> I've been taking TMG for over a year. It is very inexpensive and I think it is money well spent for many depressives. Let me tell you why. Yes TMG detoxifies homocysteine, a leading cause of heart and artery disease. But it also converts into SAMe. Studies have demonstrated that TMG raises SAME levels significantly in the body. It is actually a low cost way of increasing the bodies amount of SAMe. Both SAMe and TMG are compounds naturally found in the body. There are no side effects with it except brief muscle tension headaches if large quantities are consumed without food.
>
> Now if you want to take it, you should also be taking vitamin B6 and B12 supplements to assist in its conversion. A minimum effective dose of TMG for homocysteine reduction is 500 to 1000mg. per day. Optimal doses for SAMe elevation are about 3,000 mg/day. In some studies 6,000mgs were used. Once you start taking TMG for depression, it will probably take several weeks befroe you see results. I never saw any antidepressant effect at high doses so I now take it at just the dose for homcysteine reduction.
>
> AndrewB

Would 500mg be anadequate dose for homocysteine reduction? When do you take your TMG dose---breakfast, lunch, dinner?

So you need to supplement with B6 and B12 specifically or would a good B-50 or B100 complex do?

Thanks,
Abby


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