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Re: HELL YES!

Posted by Leighwit on April 7, 2000, at 14:45:24

In reply to Re: HELL YES!, posted by Scott L. Schofield on April 7, 2000, at 10:56:31

> > > I recently had a horrendous experience with reboxetine (Edronax, Vestra).
> > >
> > > It made my depression MUCH worse, and even put me into a state of suicidality. The only other drug that I have been taking is Lamictal 300mg. I experienced a mild worsening at 4 mg/day of reboxetine that included some anxiety, something that I usually don’t experience. After 7 days, my doctor raised the dosage to 8 mg/day. Within 48 hours, the anxiety increased and I was just about paralyzed with depression, not wanting to move a muscle. I just sat on a couch and stared at the floor. Thoughts of hopelessness and suicide filled my head. After 2 days, this stuff did not get any better, and I decided to discontinue the reboxetine. Within 48 hours of the last dose, I felt better.
> > >
> > > Has anyone else experienced a worsening of depression while taking reboxetine?
> > >
> > > If so, did this worsening disappear? Did you eventually respond to reboxetine?
> > >
> > > I would appreciate any input. Thanks,
> > >
> > >
> > > - Scott
> >

I too had problems with Reboxetine and they were somewhat similar to yours. The anxiety was quite concerning to me and like you, I'm not prone to it. Depression symptoms such as lethargy and melancholy were worsening by the day on Reboxetine, and my main response seemed to be the addition of anxiety as a new problem.

It works for some people who haven't been helped by a lot of other ADs, though, so I want to make sure we don't preclude others from trying it. By the same token, Scott — you are not alone in your experience!

Laurie (Leighwit)


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