Posted by Cam W. on February 17, 2000, at 7:09:03
In reply to Re: Gabapramide (sp?) for anxiety in alcoholism, posted by jd on February 17, 2000, at 0:43:39
> Here's a shot in the dark: Could he be thinking of gabatril, which I think is a brand name for tiagabine? Not sure if this has been released in Canada yet... Otherwise all that comes to mind is gabapentin for me too!
> --jd
>
> > > > > I was recently asked by a psychiatrist if I knew of gabapramide in the treatment of anxiety in the recovering alcoholic. I have searched Medline and the Cochrane Library, trying various spellings. My bet is that it is a drug related to buspirone, but I don't know for sure. It is supposed to be available for emergency release by the Canadian government, but when I called, all I got was the equivalent of a blank stare over the phone. Can anyone think of which drug this doc means. Thanks guys - Cam W.
> > > >
> > > > Could he have been referring to gabapentin (Neurontin)? It has been used for withdrawal-induced anxiety (see Watson, WP et al, Neuropharmacology, 1997 Oct 36(10); 1369-75. UI: 98084540.)
> > > > I have never posted to a bulletin board before, but have been reading this one for a couple of months and have found your posts (and many others') interesting and helpful. Thanks!
> > >
> > > On second thought, I don't see how Neurontin could be a restricted substance (altho I don't know anything about the Canadian system). Maybe it was GHB (gamma hydroxybutyric acid), a stimulant which can cause poisoning. It's also been used in AWS (see Addolorato, G et al. Alcohol Clin Exp Res. 1999 Oct; 23(10): 1596-604. UI: 20016183.)
> >
> > Medlib - Thanks for your help, but we know of Neurontin and GBH (also restricted in Canada). I believe gabapramide (gabipramine?) is available in
> > Europe. I know my spelling is awful, but the drug is probably a 5-HT-1A agonist. Thanks for trying, your help is much aprreciated. - Cam W.jd - Thanks, but no go again. Rechecked the spelling with the psychiatrist and it is gabapramide. The paper he saw was out of UCLA and one of his colleagues says that it available for emergency release in Canada. I phoned Health Canada and they don't have a clue. I think someone's remembering wrong, but the doc is going to try to find the paper. I will post some of it if I ever see it. Thanks again - Cam W.
poster:Cam W.
thread:21002
URL: http://www.dr-bob.org/babble/20000209/msgs/22017.html