Posted by Bruce on February 10, 2000, at 7:08:06
In reply to Re: Phosphatidylserine: Bruce, posted by andrewb on February 9, 2000, at 10:48:42
> Bruce,
>
> How does Phosphatidylserine make you feel different during exercise and during the rest of the day?
> ------------------------------------------------------------
> Blunting by chronic phosphatidylserine administration of the stress-induced activation
> of the hypothalamo-pituitary-adrenal axis in healthy men
>
> The effect of chronic administration of phosphatidylserine derived from brain cortex on the neuroendocrine responses to physical stress has
> been examined in a placebo-controlled study in 9 healthy men. Phosphatidylserine 800 mg/d for 10 days significantly blunted the ACTH and
> cortisol responses to physical exercise (P = 0.003 and P = 0.03, respectively), without affecting the rise in plasma GH and PRL. Physical
> exercise significantly increased the plasma lactate concentration both after placebo and phosphatidylserine. The results suggest that chronic oral
> administration of phosphatidylserine may counteract stress-induced activation of the hypothalamo-pituitary-adrenal axis in man.Monteleone P,
> Maj M,
Hello, Andrew! I have read your posts describing your troubles with strenuous exercise, and the inability to recover. I know *exactly* what you mean.Generally speaking, when I take PS before working out, I find two things:
1) I can work out harder and longer;
2) I do not feel the overtraining syndrome afterwards.By the overtraining syndrome I mean lethargy, inability to sleep at night, fatigue and grumpiness the next few days, etc, as usually described in the exercise literature. Note how the overtraining syndrome mimics the symptoms of depression (that is not a coincidence).
Before PS , I felt *awful* after a hard workout. My term for it was 'blasted'. It just didn't feel right. I felt old, used up. After using PS, I felt *good* after exercising, even refreshed (like the good old days before depression).
In my view, PS is a worthy adjunct to an antidepressant. I don't think it can get the job done by itself, but as an AD augmentor, it works for me. YMMV, of course. It isn't clear how much it helps in a non-exercise setting, but it may be worth a try for use on a daily basis.
I use a product from Dexter Sport Science called Powerstar Exer-Stress-PS
Try the URL
http://www.dsportscience.com/cortisol.htmlgood luck.
Bruce
poster:Bruce
thread:20696
URL: http://www.dr-bob.org/babble/20000209/msgs/20986.html