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Re: Which ADs affect dopamine and norepinephrine?

Posted by Cam W. on January 29, 2000, at 21:55:59

In reply to Re: Which ADs affect dopamine and norepinephrine?, posted by Jessica on January 29, 2000, at 19:17:18

> Every seems to like Effexor. It did nothing for me, I took it for a couple of years. I took only 75 mg a day.
>
> Is it possible to have no reaction to a medication at a low dose (i tend to only need low doses) and to have a good reaction at a greater dose?
>
> I like the sound of Wellbutrin but I'm anorexic and my doctor is a 'by the book type'.
>
> As for the MAOIs if manerix didn't work could the others? Food issues again?
>
> Could prozac help me, considering the other SSRI type medications didn't? Well, they gave me a small taste of the good life.
>
> Elavil sounds interesting.
>
> Thanks!
>
>
Jessica - Your Effexor dose was low unless you are very sensitive to the effects of antidepressants. If this is the case Prozac, because of it's long half-life (the time it takes for half the drug to leave the body) and the long half-life of it's active metabolite, may not be a good choice for you. Also Prozac's lowest dose is 10mg which may be too much for you.

Because of your sensitivity I would not recommend MAOIs, but I am more conservative in other people in their use. There are some possible cardiac problems with them and the diet it restricts you to can be a pain. I only recommend them as a last resort. They do work well in people that are refractory to other antidepressants (especially psychotic or atypical depressions) but try others first.

For an SSRI you could ask your doctor about Paxil, Zoloft or Celexa. Celexa is supposed to have the fewest side effects of the SSRIs, but people still do have side effects, especially at the initiation of treatment.

Elavil is fairly sedating, especially for about the first month. It also gives you dry mouth and dizziness and like the MAOIs, is toxic in overdose. The advantage it may have for you is that it comes in very low doses (10mg), which you can build up slowly. Researchers say that after six months of therapy the side effects that remain are similar to those that remain with the SSRIs or they disappear altogether. TCAs (like Elavil) can also cause or compound heart problems. Ask you doctor and follow his/her advice as your doctor will know your medical history, unlike me. Good luck - Cam W.


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poster:Cam W. thread:19950
URL: http://www.dr-bob.org/babble/20000128/msgs/20038.html