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Re: Which SSRI causes least sexual dysfunction in men?

Posted by Rick on October 21, 1999, at 22:28:47

In reply to Re: Which SSRI causes least sexual dysfunction in men?, posted by David on October 21, 1999, at 19:59:23

> > >
> > > No it is not a personal opinion. I read an
article (can't remember where or who wrote it
though!) where a researcher tested several ssri's
on men- and flouvoxamine had the least sexual
dysfunction side effects- my doctor also commented on Flouvoxamine in relation to the little sexual
side effects it produces.
> >
> > James here...
> >
> > Don't beleive it...every AD likes to report
this and all SSRI's have always been proven to
have sexual side effects.
> >
--------
Here's a recent study I found re the incidence of
sexual dysfunction on Luvox. The bottom line is
(where else?) at the bottom:


J Clin Psychiatry 1999 Mar;60(3):187-90

Incidence of sexual dysfunction in healthy volunteers on fluvoxamine therapy.

Nafziger AN, Bertino JS Jr, Goss-Bley AI, Kashuba AD

Clinical Pharmacology Research Center and Department of Medicine, Bassett Healthcare, Cooperstown, NY 13326-1394, USA. nafziger@iex.net

BACKGROUND: Current literature suggests that the incidence of sexual dysfunction secondary to fluvoxamine therapy is 1% to 8%, while other selective serotonin reuptake inhibitors may have rates as high as 75%. The objective of this study was to determine the incidence of sexual dysfunction secondary to fluvoxamine in healthy volunteers.

METHOD: 20 healthy volunteers (10 men, 10 premenopausal women) had adverse effects assessed at 6 visits while not receiving fluvoxamine, then twice while taking 150 mg fluvoxamine daily. Assessments occurred at 2-week intervals. Incidence rates for sexual dysfunction were calculated.

RESULTS: No sexual dysfunction was reported prior to fluvoxamine therapy. After 2 weeks and 4 weeks of therapy respectively, sexual dysfunction occurred in 20% (N = 4) and 35% (N = 7) of the healthy volunteers.

CONCLUSION: The incidence of sexual dysfunction during fluvoxamine therapy in healthy volunteers is 35%. This incidence is higher than previously reported and similar to that of other selective serotonin reuptake inhibitors.


Rick


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URL: http://www.dr-bob.org/babble/19991016/msgs/13615.html