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Re: Neurontin follow-up

Posted by Jen on September 30, 1999, at 11:06:07

In reply to Re: alternatives to Nardil: Tiagabine, Progabide?, posted by Carmen on September 28, 1999, at 13:17:35

Hi, Carmen

Yes, Nerontin is one of the new AED's. It was originally intended to be a GABA agonist, but its actual mechanism of action is unknow. For example, it doesn't increase whole brain levels of GABA. There appear to be a number of people who benefit fromm Nerontin (Gabapentin), but its efficacy is not universal across all with generalized sub-type social phobia. I've tried it up to 3600 mg/day, with no apparent effect. However, if it works for you, I'd definitely keep on it. The etiology of social phobia is still very poorly understood. Which neurotransmitters are implicated? Is there a combination of neurotransmitters? Which nerotransmitter subtypes are key? Are all the sub-type receptors known? Etc. Etc.

By the way, congratulations and my wishes for continued good luck.


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URL: http://www.dr-bob.org/babble/19990914/msgs/12316.html