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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by pretty_paints on March 14, 2005, at 7:14:11
Hiya,
Can Procyclidine make you euphoric? I'm taking three tablets in one go at the moment (15mg). It gives me this absolute bliss of calm and contentment.
I don't feel ill at all. I feel like all of my thoughts are sorted now.
I am wondering whether this could be the good effect of increasing my mirtazapine from 15mg to 30mg? It could also be clarity coming from having the Abilify increased too, to 20mg. But I don't know which!
All I know is I feel very sorted. I feel serene. Blissful. I feel quite happy. So I can't be psychotic, because I am feeling good! Normally psychosis = bad feeling. I feel like I could do anything, write a book. Yes I'm going to write a book. Everyone has been waiting for me to write one. They've been trying to pull me down and control me, but I can pull away from them and be free.
Maybe if this good feeling is due to the procyclidine, maybe it will wear off. I dunno.
Anyway.
I am missing Ed by the way! (sob). Where is he? He is like a little rabbit, gone down into the rabbit den where no-one will find him! Edddddd!!!
Anyway I have to go to jolly gardening group now. I've got the stupid Crisis Team coming round later. I think I will send them away because I am hardly in the middle of a crisis! I feel fine. Does anyone else have a Crisis Team? What do you think of them, do they make things better or worse? Do they take you out or question you a lot? Any views appreciated.
Anyway...do de do. I am off to gardening group. Hey, that nearly rhymes.
xxxxxxxxxxxxxxxxxxxxxxxxxxx
Posted by SLS on March 14, 2005, at 7:45:55
In reply to Can Procyclidine make you euphoric?, posted by pretty_paints on March 14, 2005, at 7:14:11
Anticholinergics like procyclidine are reported to have antidepressant effects for some individuals. I'm guessing that its positive effects will linger.
Good luck.
- Scott
Posted by Phillipa on March 14, 2005, at 18:24:47
In reply to Re: Can Procyclidine make you euphoric?, posted by SLS on March 14, 2005, at 7:45:55
Kate, Glad you feel good. I don't know where Ed is today. Fondly, Phillipa
Posted by ed_uk on March 15, 2005, at 6:06:45
In reply to Can Procyclidine make you euphoric?, posted by pretty_paints on March 14, 2005, at 7:14:11
Hi!
Sorry I've been ill :-( Stayed in bed all day yesterday, felt like a virus or something.
>Can Procyclidine make you euphoric?
>It gives me this absolute bliss of calm and contentment.It certainly can! In some parts of the world, anticholinergics like procyclidine are the most widely used recreational drugs! Why are you taking all three tablets at once?
Ed xx
Posted by pretty_paints on March 15, 2005, at 6:12:15
In reply to Re: Can Procyclidine make you euphoric? » pretty_paints, posted by ed_uk on March 15, 2005, at 6:06:45
Yikes! I took three at once coz it made me feel really calm and blissful. I thought that was what I was SUPPOSED to feel like "minus the akathisia", so I just thought I was getting my body back to normal. But now I see I was probably boosting the calmness and contentment ABOVE the norm.
And also because you told me I could take up to 12 a day, so I thought, that averages out to about 4 three times a day. So I was just taking 3 and then usually later I would just forget.
Okay, I will (grudingly) take them one at a time.
Posted by ed_uk on March 15, 2005, at 9:29:43
In reply to Re: Can Procyclidine make you euphoric?, posted by pretty_paints on March 15, 2005, at 6:12:15
Hi Katie!
>And also because you told me I could take up to 12 a day.
A few people take up to 60mg/day, not many people need more than 30mg though to be honest.
>blissful.
> I just thought I was getting my body back to normal.Sounds a bit better than normal to me!
How long did the effects last when you took 15mg at once?
>Okay, I will (grudingly) take them one at a time.
:-)
Ed xx
Posted by cache-monkey on March 15, 2005, at 23:31:12
In reply to Re: Can Procyclidine make you euphoric?, posted by SLS on March 14, 2005, at 7:45:55
Hi Scott,
Out of curiousity, what defines an "anticholinergic" in terms of it's physical and mental effects?
Thanks,
cache-monkey> Anticholinergics like procyclidine are reported to have antidepressant effects for some individuals. I'm guessing that its positive effects will linger.
>
> Good luck.
>
>
> - Scott
Posted by cache-monkey on March 17, 2005, at 1:13:18
In reply to Re: Can Procyclidine make you euphoric?, posted by SLS on March 14, 2005, at 7:45:55
[I'm just reposting because I forgot to tick the box to address this to Scott...]
Hi Scott,
Out of curiousity, what defines an "anticholinergic" in terms of it's physical and mental effects?
Thanks,
cache-monkey> Anticholinergics like procyclidine are reported to have antidepressant effects for some individuals. I'm guessing that its positive effects will linger.
>
> Good luck.
>
>
> - Scott
Posted by SLS on March 17, 2005, at 5:59:31
In reply to Re: Can Procyclidine make you euphoric? » SLS, posted by cache-monkey on March 17, 2005, at 1:13:18
> [I'm just reposting because I forgot to tick the box to address this to Scott...]
>
> Hi Scott,
>
> Out of curiousity, what defines an "anticholinergic" in terms of it's physical and mental effects?
>
> Thanks,
> cache-monkey
>
> > Anticholinergics like procyclidine are reported to have antidepressant effects for some individuals. I'm guessing that its positive effects will linger.
> >
> > Good luck.
An anticholinergic usually describes a drug that is capable of blocking the effects of a neurotransmitter known as acetylcholine. These drugs are used for a variety of purposes, including Parkinsons Disease and to treat the EPS side effects of antipsychotics.
- Scott
Posted by Iansf on March 17, 2005, at 21:29:54
In reply to Can Procyclidine make you euphoric?, posted by pretty_paints on March 14, 2005, at 7:14:11
From a web seminar on anitcholinergic psychosis:
The first report of abuse of an anticholinergic was reported in 1960 (Hidalgo and Mowers 1990, Land et al 1991). Over 100 cases have been reported in the literature of excessive use of benztropine, trihexyphenidyl, or procyclidine. Case reports and small studies indicate that patients experience a buzz (e.g., euphoria) and/or are more relaxed, energetic, and sociable while ingesting these compounds. Patients noted to abuse anticholinergics are more likely to have a history of polysubstance abuse and an Axis II diagnosis of antisocial personality disorder (Hidalgo and Mowers 1990). Though one report indicates that trihexyphenidyl might have a higher abuse than other anticholinergics (Hidalgo and Mowers 1990), this conclusion was not shared by other authors (Land et al 1991). Tolerance to the euphorigenic effects can occur as trihexyphenidyl doses from 15 to 2000 mg/d of have been reported (Hidalgo and Mowers 1990). It is important to note that some patients with schizophrenia increase the dose of their anticholinergic to reduce their extrapyramidal side effects (Hidalgo and Mowers 1990). If a patient with an extrapyramidal side effect is abusing anticholinergics, then an alternative treatment such as beta-blockers or amantadine might be considered (see Treatment of Extrapyramidal Side Effects handout).
This is the end of the thread.
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