Psycho-Babble Health Thread 556368

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Genetics Question, Anybody Know The Answer?

Posted by becksA on September 18, 2005, at 10:32:28

My professor gave us this to think about, I can't find the answer anywhere....
How can sex-linked disorders occur in Non-sex chromosomes?

Any ideas? Thanks a lot

Re: Genetics Question, Anybody Know The Answer? » becksA

Posted by Deneb on September 18, 2005, at 17:56:37

In reply to Genetics Question, Anybody Know The Answer?, posted by becksA on September 18, 2005, at 10:32:28

> My professor gave us this to think about, I can't find the answer anywhere....
> How can sex-linked disorders occur in Non-sex chromosomes?
>
> Any ideas? Thanks a lot

Genomic imprinting?

Functional differences between homologous alleles are determined by whether the gene is inherited by the female or male parent. The DNA methylation state of the gene involved can be passed on to the offspring.

Just going my memory here. There might be other examples.

Deneb

Just a guess... » becksA

Posted by Racer on September 28, 2005, at 12:57:07

In reply to Genetics Question, Anybody Know The Answer?, posted by becksA on September 18, 2005, at 10:32:28

> My professor gave us this to think about, I can't find the answer anywhere....
> How can sex-linked disorders occur in Non-sex chromosomes?
>
> Any ideas? Thanks a lot

Most genetic disorders are a function of multiple genes, rather than just one. In part, that's because there are usually redundancies in the genome, which protect from an awful lot of the genetic disorders -- which is why so many are recessive genes, rather than dominant.

My guess is that the sex-linked disorders in non-sex chromosomes are potentials that are only activated when they occur in conjunction with something else on a sex chromosome.

Just a guess, though. Let us know when you find out the answer?

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