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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by willyee on June 22, 2005, at 21:03:10
I know posts pop up all the time about excersise being useful.I would never argue the benifits of excersise on overall health,especialy the heart.
BUT i lift weights and have since 16,and as my anxiety grew worse i noticed my workouts are much harder.After a workout im a rockter propelled ball of adrenaline.I had to learn to pace my workouts,work on my breathing and pace myself.
I also make sure i work out before i take medication,or i render it useless.I am sure i am not the only one who finds intense excersise to agavate anxiety.Im glad i built most of my foundation when i was a teen and dident have these problems,so now im lucky enough to cut back on workouts,which i have found i HAD to do,yet not loose any gains.
Because of my anxiety i am very careful when i approach workouts,whereas as a teen i just would bang weights for hrs.A hard workout now is hard on my anxiety,i feel the pour of adrenaline,if i were recomending excersies as a therputic tool for anxiety,id prob recomend swimming.
Posted by SLS on June 22, 2005, at 21:03:10
In reply to Excercise should be approached with caution., posted by willyee on June 21, 2005, at 15:22:14
One of my doctors once said that intense anaerobic exercise like lifting weights depleted the brain of amines. If true, this type of exercise might not be best for someone who is treatment resistant and trying to maximize their chances of responding to medication.
I don't know if I agree with this. The only time I ever got well, I was engaging in some pretty intense exercise.
- Scott
Posted by Phillipa on June 22, 2005, at 21:03:10
In reply to Re: Excercise should be approached with caution., posted by SLS on June 21, 2005, at 18:05:21
Running made all my problems seem to go away. Wt lifting just makes me tired. Fondly, Phillipa
Posted by linkadge on June 22, 2005, at 21:03:10
In reply to Re: Excercise should be approached with caution., posted by Phillipa on June 21, 2005, at 18:38:50
I can't say I agree with the idea the exercise depleates amines. Aerobic exercise boosts PEA, and noradrenaline. It increases anandamide which is anticholinergic which might serve to adjust the cholinergic/adrenergic axis. It also downregulates serotonin autoreceptors which you would think would lead to more serotonin release.
It can have an overall antidopamiergic effect which might be good for some but not good for others. It certainly helps me let go of things.
Linadge
Posted by Declan on June 22, 2005, at 21:03:38
In reply to Re: Excercise should be approached with caution., posted by linkadge on June 21, 2005, at 19:18:55
My dr told me that exercise had a prodopaminergic effect (it's not all endorphins). Not right??
Declan
Posted by linkadge on June 22, 2005, at 21:03:38
In reply to Re: Excercise, dopamine and seratonin, posted by Declan on June 22, 2005, at 16:57:39
You may be right:
http://www.bio.davidson.edu/programs/HHMI04/summermentor.html
Aerobic exercise increases central dopamine concentrations and these increases are positively correlated with exercise output. Chronic exercise leads to the sustained release of dopamine and to subsequent reductions in the density of dopamine D2 receptors. It is not known whether these decreases in receptor density have functional consequences for sensitivity to psychomotor stimulants (drugs that activate central dopamine pathways to produce a host of behavioral and physiological effects). The purpose of this project is to examine the effects of exercise on sensitivity to the psychomotor stimulant cocaine in the conditioned place preference procedure, a procedure that measures the conditioned rewarding effects of drugs with abuse liability. In the proposed study, male and female rats will be obtained at weaning and reared either in standard laboratory cages or modified cages equipped with running wheels. After 6 weeks under these conditions, the conditioned rewarding effects of cocaine will be examined in both exercising and sedentary subjects, with particular attention placed on potential sex differences in these effects. A summer research assistant will be responsible for the care, training and testing of all research subjects. In addition, it is expected that the assistant will contribute to the analysis and preparation of the data for publication
----------------------------------------------It is quite possable that it has a ballancing effect on the serotogenic/dopaminergic axis.
Linkadge
Posted by SLS on June 23, 2005, at 8:34:17
In reply to Re: Excercise, dopamine and seratonin, posted by linkadge on June 22, 2005, at 17:51:19
Just to play devil's advocate:
In an interesting study, healthy people were shown how to act manic with hyperkinesis and told to act that way for varying periods of time. They did not actually become manic as a result of acting manic. However, acting manic increased dopamine turnover as measured by HVA and DOPAC present in the CSF. I don't know if the same experiment has been done with depressed individuals.
It depends where in the brain the increase in dopamine neurotransmission occurs in reaction to exercise. If it occurs predominantly in the striatum and substantia nigra, areas associated with movement, I would doubt that the elevation of DA turnover is an index of a change in mood state, but rather an index of kinesis.
- Scott
Posted by stresser on June 26, 2005, at 21:51:34
In reply to Re: Excercise should be approached with caution., posted by SLS on June 21, 2005, at 18:05:21
I have to say that I agree with Scott. -L
Posted by Declan on July 3, 2005, at 19:57:27
In reply to Re: Excercise, dopamine and seratonin, posted by SLS on June 23, 2005, at 8:34:17
Hi Scott
That must be why there are those laughter groups, I dunno if you've come across them, where people laugh for say 1 hour together. It sounds very strange, I thought like a lot of kookaburras, a bird we have here.
Declan
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