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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by mattye on December 23, 2006, at 12:36:30
Has anyone had success with St. John's Wort... or Amoryn? http://www.amoryn.com/
Posted by Phillipa on December 23, 2006, at 12:36:30
In reply to St. John's Wort / Amoryn?, posted by mattye on December 20, 2006, at 20:42:41
Amoryn on their link you provided says it's not for anxiety or dysthymia or depression. Love Phillipa
Posted by blueberry1 on December 23, 2006, at 12:36:30
In reply to St. John's Wort / Amoryn?, posted by mattye on December 20, 2006, at 20:42:41
I had good success with 600mg st johns wort added to 10mg prozac 5mg zyprexa. It was short lived and lasted about a month. It pooped out fast. I have tried st johns wort by itself two times and it did not work either time. Maybe it worked in a very slight almost undetectable way, but nothing significant. But I am a tough case.
I used the Kira brand, which is the LI160 formula in most of the clinical studies.
Posted by ronaldo on December 23, 2006, at 12:36:30
In reply to St. John's Wort / Amoryn?, posted by mattye on December 20, 2006, at 20:42:41
> Has anyone had success with St. John's Wort... or Amoryn? http://www.amoryn.com/
The Natures Medicines (the British distributor of Amoryn) website under contraindications has the following to say:
Individuals diagnosed with bipolar or manic-depressive disorder should not take AMORYN without the approval and supervision of a psychiatrist. AMORYN is not a mood-stabilizer and may increase the risk of mania.
Individuals diagnosed with schizophrenia should take AMORYN only under the close supervision of a doctor.
ronaldo
Posted by jimmygold70 on December 23, 2006, at 12:36:30
In reply to St. John's Wort / Amoryn?, posted by mattye on December 20, 2006, at 20:42:41
St. John's wort is distributed in my country as a prescription medicine. Highly standatized (I actually know the manufacturer). I know a top psychopharmacologists who prescribes it to "morons who think natural is better" (precise citation). He says it's very effective and has the same side effects as tricylic. So why not take a tricyclic in the first place? (-:
Jimmy
Posted by mattye on December 23, 2006, at 12:36:30
In reply to St. John's Wort is like tricylcics! » mattye, posted by jimmygold70 on December 22, 2006, at 4:08:21
I wasn't aware that it does the same as tricyclics. According to wikipedia, it inhibits the reuptake of GABA as well as dopamine, seretonin, and norepinepherine. Most likely, no one really knows how it works. I've just been considering it as a safe and effective add on to my normal SSRI, which would perhaps allow me to lower the dosage of my SSRI. I've heard mixed reviews ... like anything, it appears to help some people and do nothing for others.
> St. John's wort is distributed in my country as a prescription medicine. Highly standatized (I actually know the manufacturer). I know a top psychopharmacologists who prescribes it to "morons who think natural is better" (precise citation). He says it's very effective and has the same side effects as tricylic. So why not take a tricyclic in the first place? (-:
>
> Jimmy
Posted by jimmygold70 on December 23, 2006, at 12:36:30
In reply to Re: St. John's Wort is like tricylcics!, posted by mattye on December 22, 2006, at 14:00:10
It seems we know little about the real pharmacology of St. John's Wort. But if it has a nearly equivalent effect and side effect profile as some tricylcics, then it might have a similar mechanism of action. Of course, those correlations might just be coincidental.
> I wasn't aware that it does the same as tricyclics. According to wikipedia, it inhibits the reuptake of GABA as well as dopamine, seretonin, and norepinepherine. Most likely, no one really knows how it works. I've just been considering it as a safe and effective add on to my normal SSRI, which would perhaps allow me to lower the dosage of my SSRI. I've heard mixed reviews ... like anything, it appears to help some people and do nothing for others.
>
> > St. John's wort is distributed in my country as a prescription medicine. Highly standatized (I actually know the manufacturer). I know a top psychopharmacologists who prescribes it to "morons who think natural is better" (precise citation). He says it's very effective and has the same side effects as tricylic. So why not take a tricyclic in the first place? (-:
> >
> > Jimmy
>
>
Posted by linkadge on December 24, 2006, at 12:12:38
In reply to Re: St. John's Wort is like tricylcics! » mattye, posted by jimmygold70 on December 22, 2006, at 16:29:05
I wouldn't consider it identical to TCA's.
For starters, in mice SJW is a smart drug. It lacks prominant anticholingeric side effects. Its nootropic action may be mediated by sigma recptors.
In addition, SJW is not directly cardiotoxic like the TCA's.
So if they both work about as well, why not keep your cognition and your cardiac function??
Linkadge
Posted by Meri-Tuuli on January 9, 2007, at 10:33:08
In reply to Re: St. John's Wort is like tricylcics!, posted by linkadge on December 24, 2006, at 12:12:38
Well said Link.
I personally think you can't compare SJW with a TCA either. For starters, SJW lacks the side effect profile of the TCAs, which in itself is a blessing.
Its like comparing a super snazzy sports car to an old banger - yes, both get you from A to B, but are completely different really.
M
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