Posted by jimmygold70 on December 22, 2006, at 16:29:05 [reposted on December 23, 2006, at 12:36:30 | original URL]
In reply to Re: St. John's Wort is like tricylcics!, posted by mattye on December 22, 2006, at 14:00:10
It seems we know little about the real pharmacology of St. John's Wort. But if it has a nearly equivalent effect and side effect profile as some tricylcics, then it might have a similar mechanism of action. Of course, those correlations might just be coincidental.
> I wasn't aware that it does the same as tricyclics. According to wikipedia, it inhibits the reuptake of GABA as well as dopamine, seretonin, and norepinepherine. Most likely, no one really knows how it works. I've just been considering it as a safe and effective add on to my normal SSRI, which would perhaps allow me to lower the dosage of my SSRI. I've heard mixed reviews ... like anything, it appears to help some people and do nothing for others.
>
> > St. John's wort is distributed in my country as a prescription medicine. Highly standatized (I actually know the manufacturer). I know a top psychopharmacologists who prescribes it to "morons who think natural is better" (precise citation). He says it's very effective and has the same side effects as tricylic. So why not take a tricyclic in the first place? (-:
> >
> > Jimmy
>
>
poster:jimmygold70
thread:715897
URL: http://www.dr-bob.org/babble/alter/20061218/msgs/715903.html