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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 16 of 16. This is the beginning of the thread.
Posted by joe f on May 5, 2019, at 15:40:25
because of the opiod cris benzos seem to be getting a lot of press.....has anyone had the experience of a dr . just stopping them without weaning......and i still cannot believe no one uses rexulti....where i go they are pushing it like candy
Posted by Christ_empowered on May 6, 2019, at 9:50:47
In reply to doctors stopping benzos, posted by joe f on May 5, 2019, at 15:40:25
doctors are -really- not supposed to just cut off benzodiazepines, without putting a tapering plan in place. is that happening to you?
on other forums, i've noticed a number of people prescribed rexulti. the other one...vraylar or whatever...seems less popular, but i could be wrong.
Posted by SLS on May 6, 2019, at 11:20:52
In reply to Re: doctors stopping benzos, posted by Christ_empowered on May 6, 2019, at 9:50:47
> doctors are -really- not supposed to just cut off benzodiazepines, without putting a tapering plan in place. is that happening to you?
>
> on other forums, i've noticed a number of people prescribed rexulti. the other one...vraylar or whatever...seems less popular, but i could be wrong.I tried both Rexulti and Vraylar. Rexulti is chemically related to Abilify, which I have derived some benefit from in the past. However, Rexulti was of no benefit to me. Vraylar, on the other hand, made my depression much more severe.
My chronic depression probably lies somewhere along the bipolar spectrum. Some antidepressant treatments have launched me into a severe and psychotic mania. The DSM 5 now includes this presentation in its description of bipolar disorder.
- Scott
Posted by Christ_empowered on May 6, 2019, at 13:02:39
In reply to Re: doctors stopping benzos, posted by SLS on May 6, 2019, at 11:20:52
sorry about that, sls.
i think...vrayralar (probably not spelled correctly)...is the one that has the high(ish) EPS? that might explain why it exacerbated your depression. personally...
now that i stop and think about it for a second, my own "bipolar depression" seems to get worse on tranquilizers with higher EPS liability. my best, wild *ss guess is that the EPS potential is probably related to the neuroleptic induced dysphoria and/or neuroleptic induced deficit syndrome severity, too.
just a thought. how's treatment going for you, now?
Posted by joe f on May 6, 2019, at 15:22:30
In reply to Re: doctors stopping benzos, posted by Christ_empowered on May 6, 2019, at 13:02:39
to be honest i stayed at 250 luvox 2mg of rexulti went to 10 adderal 2x daiy from 7.5 and 15 valium and 5 in day and feel pretty good ....but lost my part time job due to closing and too much time on my hands......will have to find something part time
Posted by SLS on May 6, 2019, at 16:01:30
In reply to Re: doctors stopping benzos, posted by Christ_empowered on May 6, 2019, at 13:02:39
Hi, C_E.
> just a thought. how's treatment going for you, now?I have been taking Trintellix (vortioxetine) at 10 mg/day for 4 weeks. From what I understand, Trintellix takes a little longer to work than most other antidepressants (6-8 weeks). I have experienced mild, but unambiguous improvements. They have been episodic and last for only a few days. I am trying to be cautious in my optimism.
Have you found stability in your treatment? Are you still taking 30 mg/day of Abilify?
- Scott
Posted by joe f on May 6, 2019, at 16:05:51
In reply to Re: doctors stopping benzos, posted by SLS on May 6, 2019, at 16:01:30
no 2 mg of rexulti instead of abilify
Posted by Christ_empowered on May 6, 2019, at 18:41:08
In reply to Re: doctors stopping benzos, posted by joe f on May 6, 2019, at 16:05:51
hey sls...
I'm on 20mgs/Abilify now. the latest doctor at the clinic added 20mgs/Prozac. I've only been on the Prozac for maybe 2 weeks, and I actually do feel less anxious, I think my mood has improved, etc.
thanks for asking. I hope the Trintellix works out nicely for you. have you ever been prescribed Ritalin (or Focalin, these days) to help your mood and energy levels? Just a thought.
Posted by sigismund on May 7, 2019, at 1:53:43
In reply to Re: doctors stopping benzos, posted by SLS on May 6, 2019, at 16:01:30
Scott, you tried it before and it made things much worse?
That was a higher dose, right? What was that?
Posted by SLS on May 7, 2019, at 10:42:09
In reply to Re: doctors stopping benzos » SLS, posted by sigismund on May 7, 2019, at 1:53:43
> Scott, you tried it before and it made things much worse?
>
> That was a higher dose, right? What was that?You have a great memory. Thanks for asking.
Last year, I discontinued Parnate rather abruptly. I allowed myself only 14 days to taper from 100 mg/day to zero. I experienced a severe worsening of depression with anxiety. It was more severe than my baseline depressive state, and most likely a rebound effect. I began Trintellix after a 10 day washout. I think that I was taking 20 mg/day until I experienced a weird reaction 10 days into treatment. I felt dazed and confused. I was in a fog and couldn't think straight. My memory was terrible. I felt like my eyes were open too wide, and I stared into space. I would remain motionless for minutes at a time. I was altered. I concluded that this state was a negative reaction to Trintellix, and I stopped taking it after being on it for only 10 days. However, I experienced the same intense reaction to my subsequent trials of Effexor and Nardil. I returned to Parnate out of desperation, and the altered state slowly dissipated. Unfortunately, I ended up back where I started. Parnate helps with energy and cognition, but leaves me with a barren existence. My doctor thought that my negative reactions to Trintellix, Effexor, and Nardil were caused by my abrupt discontinuation of Parnate. I urged my doctor to retry Trintellix, but only after a very slow taper from Parnate. I allowed for over two months to taper and discontinue it entirely. I reduced the daily dosage by 10 mg every week or so.
I restarted Trintellix at 5 mg/day. After one week, I raised the dosage to 10 mg/day. I have remained there for over a month. My doctor seems to think that less is more with Trintellix, and that it usually takes 6-8 weeks to begin working. Yesterday, I felt uncharacteristically good for the first half of the day, but faded by late afternoon. I experienced similar improvements for a few days when I first started Trintellix and upon the dosage increase. I am scared to hope.
What's been going on with you? I always find your posts on the other boards intriguing, but they are usually beyond my scope of knowledge.
- Scott
Posted by Roslynn on May 8, 2019, at 14:18:53
In reply to Re: doctors stopping benzos » sigismund, posted by SLS on May 7, 2019, at 10:42:09
I remember this, and I was very worried about you, but unsure of what I could do. So glad to hear things are at least a little better.
Roslynn
Posted by SLS on May 8, 2019, at 21:16:12
In reply to Re: doctors stopping benzos » SLS, posted by Roslynn on May 8, 2019, at 14:18:53
Posted by sigismund on May 9, 2019, at 1:39:55
In reply to Re: doctors stopping benzos » sigismund, posted by SLS on May 7, 2019, at 10:42:09
Some days are better than others, I'm OK, not enthusiastic and have thought about going on a similar dose of the drug you are on.
I do take saffron, ginkgo and other things that don't really work :)
Posted by Jeroen on May 14, 2019, at 8:47:09
In reply to Re: doctors stopping benzos, posted by SLS on May 6, 2019, at 11:20:52
Hi Scott, the only thing that worked was minocycline after 3 days I was in remission, please need your help
on Saphris 15 mg right now, still depressed however not psychotic
Please help
Posted by SLS on May 15, 2019, at 10:57:18
In reply to TO SLS please get back to me friend, posted by Jeroen on May 14, 2019, at 8:47:09
> Hi Scott, the only thing that worked was minocycline after 3 days I was in remission, please need your help
>
> on Saphris 15 mg right now, still depressed however not psychotic
>
> Please help
Minocycline does several things that might reduce depression and negative symptoms of schizophrenia.1. Reduces inflammation by inhibiting the release of microglial pro-inflammatory cytokines.
2. Prevents neuron death by reducing glutamate release and overactivity.
3. Stimulates neuronal growth by increasing nerve growth factor (NGF).You might want to look for substances or drugs that do some of these things.
Have you tried N-acetylcysteine - NAC?
Does lamotrigine (Lamictal) cause you to become psychotic? Did your depression or negative symptoms improve just before the psychosis appeared?
- Scott
Posted by Jeroen on May 15, 2019, at 13:27:54
In reply to Re: TO SLS please get back to me friend » Jeroen, posted by SLS on May 15, 2019, at 10:57:18
N-acetylcysteine - NAC? yes I've tried made me relax in the beginning then got vertigo attacks after a week and half into it did nothing for everything
lamictal caused my psychotic thing yes that i still have today. no nothing improved just psychosis
This is the end of the thread.
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