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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 17 of 17. This is the beginning of the thread.
Posted by Lamdage22 on October 1, 2016, at 12:39:46
What if Seroquel+ Zyprexa poops out? Clozapine? I dont have weight gain anymore. I am actually almost normal weight now.
Posted by SLS on October 1, 2016, at 14:34:38
In reply to Poop out. And then?, posted by Lamdage22 on October 1, 2016, at 12:39:46
> What if Seroquel+ Zyprexa poops out? Clozapine? I dont have weight gain anymore. I am actually almost normal weight now.
What happens when these drugs poop-out on you? What symptoms emerge?
I forget your diagnosis.
- Scott
Posted by Christ_empowered on October 1, 2016, at 14:43:44
In reply to Poop out. And then?, posted by Lamdage22 on October 1, 2016, at 12:39:46
I read that some anticonvulsants (I wanna say they suggested Lamictal) can prevent brain changes that lead to increased dosages and/or "treatment resistance."
Some people can maintain or lower neuroleptic dosage with an anticonvulsant, even a carefully dosed benzodiazepine.
Posted by rjlockhart37 on October 2, 2016, at 2:26:25
In reply to Poop out. And then?, posted by Lamdage22 on October 1, 2016, at 12:39:46
if they both stop working, there's geodon, saphris, and various others new generation AP's.... it would be more of risk to move to clozapine because it's potent, and if you ever had a resistant effect to it, options would be limited, you would only be left with the old harsh generation anti-psychotics.....or haloperidol
my suggestion is work with the dosages you have on zyprexa and seroquel, maybe increase trazadone, your doctor has to work with you on this, we can only give suggestions on babble, only suggestion you could talk to your doctor
keep us updated
r
Posted by Lamdage22 on October 2, 2016, at 3:54:29
In reply to Re: Poop out. And then? » Lamdage22, posted by SLS on October 1, 2016, at 14:34:38
> > What if Seroquel+ Zyprexa poops out? Clozapine? I dont have weight gain anymore. I am actually almost normal weight now.
>
> What happens when these drugs poop-out on you? What symptoms emerge?
>
> I forget your diagnosis.
>
>
> - ScottWell if they poop out i am anxious and psychotic. Schizoaffective. I take maximum Zyprexa now 20mg and 1000mg Seroquel.
Posted by Lamdage22 on October 2, 2016, at 3:57:47
In reply to Re: Poop out. And then?, posted by Lamdage22 on October 2, 2016, at 3:54:29
I wonder if i sould try valproic acid or Remeron.
Posted by SLS on October 2, 2016, at 7:18:30
In reply to Re: Poop out. And then?, posted by Lamdage22 on October 2, 2016, at 3:54:29
> > > What if Seroquel+ Zyprexa poops out? Clozapine? I dont have weight gain anymore. I am actually almost normal weight now.
> >
> > What happens when these drugs poop-out on you? What symptoms emerge?
> >
> > I forget your diagnosis.
> >
> >
> > - Scott
>
> Well if they poop out i am anxious and psychotic. Schizoaffective. I take maximum Zyprexa now 20mg and 1000mg Seroquel.I know someone who has schizoaffective disorder who did not achieve remission with a combination of Abilify ? mg/day and Seroquel 900 mg/day. Her presentation is one of the bipolar types. She would become psychotic with some paranoia; the theme being that there was an intruder in the house. Nothing seemed to work well for her, and she ended up being hospitalized several times. Then, a very inciteful doctor decided to put her on Navan (thiothixene). This cleared up the psychosis well. However, there was some residual depression. She remained on Navane and Sapris (asenapine) was added. This turned on the light for her. It cleared up her thinking and was energizing. The net effect is that she achieved full remission and lost all of the Abilify + Seroquel weight gain. My doctor thinks that Saphris is particularly good for treating cases where paranoia exists. Saphris does have antidepressant properties.
If you are not too keen to move to Navane at this juncture, then I would consider switching from Seroquel to Saphris. Zyprexa is often the second best of the atypical neuroleptic antipsychotics; Clozaril being the first. Of course, this is not universally true. It is amazing, but a real pain in the butt, that two people will respond differently to the same drug. I think it may be too early to go to Clozaril and deal with weekly or biweekly blood tests to screen for agranulocytosis (neutrophils).
Let me know what you think.
- Scott
Posted by Lamdage22 on October 2, 2016, at 11:20:21
In reply to Re: Poop out. And then? » Lamdage22, posted by SLS on October 2, 2016, at 7:18:30
Hi Scott,
first let me say that you are awesome taking the time out of your day to help.
Yes i could certainly ask for saphris is what i think. Germany doesnt have it approved for schizophrenia but only for mania, but i think my doc is not too scared to try to use it off label (off german label at least).
Navane: Is it as nasty as Haloperidol with side effects?
THX
> > Well if they poop out i am anxious and psychotic. Schizoaffective. I take maximum Zyprexa now 20mg and 1000mg Seroquel.
>
> I know someone who has schizoaffective disorder who did not achieve remission with a combination of Abilify ? mg/day and Seroquel 900 mg/day. Her presentation is one of the bipolar types. She would become psychotic with some paranoia; the theme being that there was an intruder in the house. Nothing seemed to work well for her, and she ended up being hospitalized several times. Then, a very inciteful doctor decided to put her on Navan (thiothixene). This cleared up the psychosis well. However, there was some residual depression. She remained on Navane and Sapris (asenapine) was added. This turned on the light for her. It cleared up her thinking and was energizing. The net effect is that she achieved full remission and lost all of the Abilify + Seroquel weight gain. My doctor thinks that Saphris is particularly good for treating cases where paranoia exists. Saphris does have antidepressant properties.
>
> If you are not too keen to move to Navane at this juncture, then I would consider switching from Seroquel to Saphris. Zyprexa is often the second best of the atypical neuroleptic antipsychotics; Clozaril being the first. Of course, this is not universally true. It is amazing, but a real pain in the butt, that two people will respond differently to the same drug. I think it may be too early to go to Clozaril and deal with weekly or biweekly blood tests to screen for agranulocytosis (neutrophils).
>
> Let me know what you think.
>
>
> - Scott
Posted by Jeroen on October 11, 2016, at 9:16:28
In reply to Poop out. And then?, posted by Lamdage22 on October 1, 2016, at 12:39:46
i hope for you it wont poop out
Posted by Lamdage22 on October 11, 2016, at 9:18:06
In reply to Re: Poop out. And then?, posted by Jeroen on October 11, 2016, at 9:16:28
> i hope for you it wont poop out
Thanks, Jeroen. I am currently on about 1k of Seroquel and 20mg of Zyprexa. Non psychotic. So both are maxed out although i know that some doctors go higher. I take a cyp3a4 inhibitor, thats why i take so much Seroquel.
Posted by Jeroen on October 11, 2016, at 9:29:47
In reply to Re: Poop out. And then?, posted by Lamdage22 on October 11, 2016, at 9:18:06
this dosage would kill me!!!!
Posted by Lamdage22 on October 11, 2016, at 9:30:34
In reply to 1K seroquel is high man, posted by Jeroen on October 11, 2016, at 9:29:47
im like a horse you know? Just kidding.
Posted by Jeroen on October 11, 2016, at 9:32:50
In reply to Re: 1K seroquel is high man, posted by Lamdage22 on October 11, 2016, at 9:30:34
yes indeed
Posted by Lamdage22 on October 11, 2016, at 14:12:13
In reply to yes indeed, posted by Jeroen on October 11, 2016, at 9:32:50
Its not much different from taking 700-800mg since i am on the CYP3A4 inhibitor. Its still a high dose but yeah. I wanted to quit everything once in 2013 and since then i need the high dosage of Seroquel and Zyprexa. I have damaged myself in a way with that.
Posted by Jeroen on October 11, 2016, at 14:21:16
In reply to yes indeed, posted by Jeroen on October 11, 2016, at 9:32:50
too bad this kind of sh*t happens with everyone : (
Posted by Christ_empowered on October 11, 2016, at 18:56:40
In reply to Re: yes indeed, posted by Lamdage22 on October 11, 2016, at 14:12:13
Have you thought about choosing 1 neuroleptic and then adding in some kind of mood stabilizer? I did read that Lamictal is supposed to be good for long term neuroleptic treatment...I forget how, but its supposed to make the AP/AAP work better and prevent dosage escalation over time. There's info on it at the mad in america website.
Are you getting your eyes checked? Apparently, seroquel really can damage one's vision. I would think it'd be worse at high doses.
Are you sedated? I'm amazed that you aren't asleep 24/7. I struggle some with concentration and sedation on my lil cocktail, but I don't think its near as sedating as all that seroquel+zyprexa. Wow. You're a champ...
Posted by Lamdage22 on October 12, 2016, at 3:24:53
In reply to Re: yes indeed, posted by Christ_empowered on October 11, 2016, at 18:56:40
lamictal doesnt work for me
This is the end of the thread.
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