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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by Lamdage22 on May 16, 2014, at 8:29:35
I take 700mg of Seroquel and 15mg of Zyprexa.
Should i add low dose Haldol?
Im really in a funk lately.
Posted by Christ_empowered on May 16, 2014, at 9:22:21
In reply to Stablon gone bad. Psychotic symptoms back! Haldol?, posted by Lamdage22 on May 16, 2014, at 8:29:35
wow. that's an intense combo you got there. I was thinking a low dose of Abilify, or maybe something...not...haloperidol, lol.
Ever tried loxapine? Do they have that where you are? Its atypical at low doses. Maybe add a bit of that, or maybe do abilify+loxapine, for less sedation?
Posted by Phillipa on May 16, 2014, at 9:33:49
In reply to Stablon gone bad. Psychotic symptoms back! Haldol?, posted by Lamdage22 on May 16, 2014, at 8:29:35
Are you at home? Germany? Phillipa
Posted by Jeroen on May 16, 2014, at 13:08:14
In reply to Re: Stablon gone bad. Psychotic symptoms back! Haldol?, posted by Christ_empowered on May 16, 2014, at 9:22:21
loxapine an atypical???
Posted by Christ_empowered on May 16, 2014, at 14:25:57
In reply to loxapine an atypical???, posted by Jeroen on May 16, 2014, at 13:08:14
supposedly, at low doses. similarly, amoxapine, an antidepressant that partly metabolizes to--you guessed it--loxapine might be an atypical antipsychotic at sufficient doses.
Posted by phidippus on May 16, 2014, at 16:37:53
In reply to Stablon gone bad. Psychotic symptoms back! Haldol?, posted by Lamdage22 on May 16, 2014, at 8:29:35
I don't know what adding haldol will do for you.
Eric
Posted by Lamdage22 on May 17, 2014, at 12:12:56
In reply to Re: Stablon gone bad. Psychotic symptoms back! Haldol?, posted by Christ_empowered on May 16, 2014, at 9:22:21
They have loxapine for inhalation!
Phillipa, im in Germany..
What would be the advantage over Haldol?
My doc said Seroquel and Zyprexa were very similar in what they are doing and it may not be efficient to combine the two for that reason.
She also suggested amisulpirid!
I took Melperon once.
Posted by phidippus on May 17, 2014, at 17:16:21
In reply to Re: Stablon gone bad. Psychotic symptoms back! Haldol?, posted by Lamdage22 on May 17, 2014, at 12:12:56
What is the nature of your symptoms?
I would do the Haldol instead of Zyprexa.
Loxapine is a typical antipsychotic medication, used primarily in the treatment of schizophrenia. Trade names for loxapine taken by mouth include Loxapac and Loxitane; the inhalable form is approved as Adasuve. The drug is a member of the dibenzoxazepine class and structurally related to clozapine. Several researchers have argued that loxapine may behave as an atypical antipsychotic.
~Wikipedia
Here is its binding profile:5-HT1A 2456
5-HT1B 388
5-HT1D 3468
5-HT1E 1399
5-HT2A 6.63
5-HT2C 13.3
5-HT3 190
5-HT5A 776
5-HT6 31.0
5-HT7 87.6
α1A 31
α1B 53
α2A 150.9
α2B 107.8
α2C 80.0
β1 >10000
β1 >10000
M1 119.5
M2 445
M3 211.3
M4 1266
M5 166
D1 54
D2 11
D3 19.33
D4 8.4
D5 75
H1 4.9
H2 208
H4 5048
SERT >10000
NET 5698
DAT >10000There is no real advantage over Haldol.
Eric
Posted by Christ_empowered on May 17, 2014, at 21:52:35
In reply to Re: Stablon gone bad. Psychotic symptoms back! Haldol? » Lamdage22, posted by phidippus on May 17, 2014, at 17:16:21
Haldol is partly metabolized to a neurotoxic compound. This might explain why even low-ish doses routinely produce TD.
I'd take perphenazine, loxapine, amoxapine (high dose) over Haldol.
Posted by Lamdage22 on May 18, 2014, at 3:31:24
In reply to haldol?!?, posted by Christ_empowered on May 17, 2014, at 21:52:35
Okay i will restrain from Haldol.
Yesterday i took 900mg Seroquel and 25mg of Zyprexa.
That does the trick, too.
How long do you think am i still affected by the Stablon trial? Its been like 10to 12 days.
This is the end of the thread.
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