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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by kribensis on April 21, 2014, at 19:40:06
Has anyone taken both these meds (not at the same time but taken both to compare the two...)?
Having problems finding a med that works. Just to clarify (if someone has read my other posts), I initially started effexor because it worked for me in past, took for 8 days and then stopped as my dr mentioned moclobemide and thought it might be a good fit with less side effects. Tried moclobemide only for a couple of days but felt terrible. Now I think that was from stopping the effexor even though I was only on it for 8 days.
Trying to decide if mocolobemide is worth another try? Looking for something to help me with energy and motivation as well as some depression.
Also toying with trying cymbalta. Trying to find a med that works is proving to be more difficult than I thought.
Posted by LouisianaSportsman on April 21, 2014, at 23:52:34
In reply to moclobemide versus effexor XR, posted by kribensis on April 21, 2014, at 19:40:06
started effexor because it worked for me in past, took for 8 days and then stopped
>If it worked for you in the past, why did you stop?
Also, why did your doctor not place you on another AD then and titrate you off venlafaxine if you are prone to discontinuation syndrom?
I believe you should stick with the Effexor XR; if you insist, moclobermide is not a bad option, but venlafaxine lacks diet restrictions and other side effects.
Posted by kribensis on April 22, 2014, at 2:59:16
In reply to Re: moclobemide versus effexor XR, posted by LouisianaSportsman on April 21, 2014, at 23:52:34
I didn't think there was dietary restrictions with a normal dosage of moclobemide?
Long story re: effexor. It has been about 5 years since I was one it. Weaned off after feeling like it wasn't effective anymore and didn't think I needed it. Recently went through/am going through a stressful time like I can't cope, have done everything natural to help myself.
Effexor comes along with side effects that I would like to avoid if possible. If nothing else works, I will give it another shot. Dr gave me effexor rx with option to look at mocolbemide (I had never heard of it before). Didn't realize that I would have withdrawal effects after only taking it for a week.
Posted by Louisiana Sportsman on April 22, 2014, at 12:50:23
In reply to Re: moclobemide versus effexor XR, posted by kribensis on April 22, 2014, at 2:59:16
I didn't think there was dietary restrictions with a normal dosage of moclobemide?
>I apologize. I've spent a little bit of time on Google Scholar reading about moclobemeide. The only reason I am uneducated about it is because it isn't offered in the United States, honestly. I just made a wrong assumption. Amateur hour.
> Long story re: effexor. It has been about 5 years since I was one it. Weaned off after feeling like it wasn't effective anymore and didn't think I needed it. Recently went through/am going through a stressful time like I can't cope, have done everything natural to help myself.
> Effexor comes along with side effects that I would like to avoid if possible. If nothing else works, I will give it another shot. Dr gave me effexor rx with option to look at mocolbemide (I had never heard of it before). Didn't realize that I would have withdrawal effects after only taking it for a week.
Hmm, I guess it's nice to have a malicious, yet effacious, venlafaxine backup. Dizziness, nausea and insomnia occurrs more frequently on moclobemide than on placebo, and I know you have a problem with nausea, or at least gastrointestinal discomfort with modafinil; I hope the same problem doesn't carry over to mocolobemide.
Too bad venlafaxine is not a suggested augmentation agent for moclobemide, have there been any SSRIs that have worked?
I think mianserin would be a fantastic combination with moclobemide.
Go ahead and try the moclobemide now that I have a better understanding of your situation; if you have only negligible benefits, consider mianserin (or the SSRI that has worked best for you in the past, if applicable).
If you do decide to try moclobemide, please share your experience on the forum!
Good luck with your treatment.
Posted by kribensis on May 2, 2014, at 17:46:28
In reply to Re: moclobemide versus effexor XR, posted by Louisiana Sportsman on April 22, 2014, at 12:50:23
There has not been a SSRI that worked for me.
I took sibutramine for a period of time and it was brilliant- the best thing for my depression that I have ever found (no longer available), what would be the closest?
Anyhow, I am on about day 10 of moclobemide. I really don't know about this, am discouraged.
I am a bit up and down on it so the up part it good but I don't really find it energizing at all (which is what I was hoping for). If anything I am actually more tired, sleeping better (which is good but too sleepy during the day). I don't know if it would help at taking it at night. With the short half life I'm wondering if that would do anything at all.
I'm only up to 450mg so far. Anything more than that and the nausea in my head it too much to function so I'm trying to bump up slowly.
I know many people have found it takes up to 8 weeks for this to work but I tend to either respond well in a week or the drug doesn't work even if I stay on longer (from experience in the past).
I am feeling really lost, discouraged, and frustrated. I don't know if I should stick this out or drop it and try Pristiq. I also wonder if adding low dose naltrexone would do anything.
Posted by kribensis on May 2, 2014, at 18:06:34
In reply to Re: moclobemide versus effexor XR » Louisiana Sportsman, posted by kribensis on May 2, 2014, at 17:46:28
Just wanted to add that when I say 'up and down' the ups aren't even really up, it just means that I can actually do stuff without feeling like I want to be lying in bed staring at the wall. A positive is that I think it somewhat helps my focus.
This is the end of the thread.
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