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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 25 of 26. This is the beginning of the thread.
Posted by Phil on April 2, 2013, at 13:39:38
Been reading the archives on Metformin and seems to help with some weight loss. A bit?
I'm not working, sedentary, and over the last 8-10 years gained 50 pounds. Thank you Zyprexa and Seroquel.
I'm trying to pack up stuff for a move and I have 0 energy. It's either Metformin or drop Seroquel, I can't live like this and the heavier I get and the depression from it, it just makes the whole exercise thing seem like a joke.
I'm not frustrated I'm pissed off.
Posted by Phil on April 2, 2013, at 14:25:24
In reply to Called doc--Metformin please, posted by Phil on April 2, 2013, at 13:39:38
My doc puzzles me. I asked him about how Seroquel works in the brain last week and I wasn't overly thrilled with his convoluted answer.
He just called back on my metformin inquiry and needs some time to look into it. I understand taking a look at my chart but hasn't he had this question before?
I feel like I'm talking to myself. I'm used to it.
Posted by Phil on April 2, 2013, at 15:02:10
In reply to Re: Called doc--Metformin please, posted by Phil on April 2, 2013, at 14:25:24
http://jama.jamanetwork.com/article.aspx?articleid=1380162
Conclusions: Lifestyle intervention and metformin alone and in combination demonstrated efficacy for antipsychotic-induced weight gain. Lifestyle intervention plus metformin showed the best effect on weight loss. **Metformin alone was more effective in weight loss and improving insulin sensitivity than lifestyle intervention alone.**
Posted by Phillipa on April 2, 2013, at 15:20:06
In reply to Re: Called doc--Metformin please, posted by Phil on April 2, 2013, at 15:02:10
Phil can you get it online? Anyone you know on it? Phillipa
Posted by Phil on April 2, 2013, at 15:34:58
In reply to Re: Called doc--Metformin please » Phil, posted by Phillipa on April 2, 2013, at 15:20:06
My brother is on it but I don't think I'll ask him for his script. I don't buy drugs online. I think my doc will write it.
Posted by Toph on April 2, 2013, at 18:15:03
In reply to Called doc--Metformin please, posted by Phil on April 2, 2013, at 13:39:38
Posted by Phil on April 2, 2013, at 20:14:34
In reply to Are you diabetic (nm) » Phil, posted by Toph on April 2, 2013, at 18:15:03
Not yet.
Posted by Phil on April 2, 2013, at 20:49:31
In reply to Are you diabetic (nm) » Phil, posted by Toph on April 2, 2013, at 18:15:03
There are quite a few
Posted by Phillipa on April 2, 2013, at 20:55:03
In reply to Another study, Metformin for AAP obesity » Toph, posted by Phil on April 2, 2013, at 20:49:31
Phil glad your doc will write a script. I wouldn't buy meds online either unless with a script. Phillipa
Posted by Phil on April 3, 2013, at 7:32:38
In reply to Are you diabetic (nm) » Phil, posted by Toph on April 2, 2013, at 18:15:03
Posted by tensor on April 3, 2013, at 15:29:17
In reply to Another study, Metformin for AAP obesity » Toph, posted by Phil on April 2, 2013, at 20:49:31
> There are quite a few
>
> http://www.ncbi.nlm.nih.gov/pubmed/22225552http://www.ncbi.nlm.nih.gov/pubmed/22398127
http://www.ncbi.nlm.nih.gov/pubmed/21284696
http://www.utexas.edu/pharmacy/divisions/pharmaco/rounds/01-20-11.pdf
http://psychiatristupdate.wordpress.com/tag/metformin-in-antipsychotic-induced-weight-gain/
http://www.medscape.org/viewarticle/568577/tensor
Posted by Phil on April 4, 2013, at 11:44:29
In reply to Re: Another study, Metformin for AAP obesity » Phil, posted by tensor on April 3, 2013, at 15:29:17
My doc called, 500 mg Metformin twice a day. It's a start. It's hope. That's all I want to kick this into gear.
Posted by Phil on April 4, 2013, at 13:59:19
In reply to My doc called WIN!! » tensor, posted by Phil on April 4, 2013, at 11:44:29
The first doc that put me on AP's and started seeing weight gain should have put me on it then. It's best at stopping further weight gain.. OK, enough of this.
Posted by tensor on April 4, 2013, at 14:01:51
In reply to My doc called WIN!! » tensor, posted by Phil on April 4, 2013, at 11:44:29
> My doc called, 500 mg Metformin twice a day. It's a start. It's hope. That's all I want to kick this into gear.
Good news, keep us posted on your progress!
/tensor
Posted by Toph on April 5, 2013, at 14:24:37
In reply to ?? (nm) » Toph, posted by Phil on April 3, 2013, at 7:32:38
I asked Phil because I am used to seeing Metformin used in the treatment of diabetes. I did not know it had another use.
Posted by Phil on April 5, 2013, at 15:38:13
In reply to Re: ?? » Phil, posted by Toph on April 5, 2013, at 14:24:37
Posted by andrewb on April 14, 2013, at 21:37:40
In reply to Thanks Toph (nm) » Toph, posted by Phil on April 5, 2013, at 15:38:13
Good luck with the Metformin. It not only may help control your weight but also it should help prevent diabetes from developing. Seroquel elevates prolactin (via D2 antagonism) and elevated prolactin causes insulin resistance. This insulin resistance will cause weight gain and, given enough time, lead to diabetes. The ideal dose of Metformin for you may be 2000mg/day or so, in the extended release form ideally. It might cause your stomach to feel upset at first, give this time to go away. Follow up with an insulin resistance test (not a glucose tolerance test) to make sure this issue has been dealt with.
Posted by SLS on April 15, 2013, at 6:22:51
In reply to Seroquel, Metformin and Insulin Resistance, posted by andrewb on April 14, 2013, at 21:37:40
Hi.
:-)
- Scott
Posted by SLS on April 15, 2013, at 6:23:34
In reply to Seroquel, Metformin and Insulin Resistance, posted by andrewb on April 14, 2013, at 21:37:40
How are you?
- Scott
Posted by Phil on April 15, 2013, at 13:35:40
In reply to Seroquel, Metformin and Insulin Resistance, posted by andrewb on April 14, 2013, at 21:37:40
Posted by andrewb on April 16, 2013, at 10:41:19
In reply to Re: Seroquel, Metformin and Insulin Resistance » andrewb, posted by SLS on April 15, 2013, at 6:23:34
> How are you?
> - ScottVery good, thanks for asking. Sometimes good things happen when you aren't expecting them! Tender mercies from unseen places perhaps.
By the way, when I log on I look for your posts. I'm always rooting for you. Over the years, no matter how you have felt at the time, you have always displayed good character. That is something that never can be taken away.
Andy
Posted by SLS on April 16, 2013, at 14:42:12
In reply to Re: Seroquel, Metformin and Insulin Resistance, posted by andrewb on April 16, 2013, at 10:41:19
> > How are you?
> > - Scott
>
> Very good, thanks for asking. Sometimes good things happen when you aren't expecting them! Tender mercies from unseen places perhaps.
> By the way, when I log on I look for your posts. I'm always rooting for you. Over the years, no matter how you have felt at the time, you have always displayed good character. That is something that never can be taken away.
> Andy
Thank you for your kind sentiments and generous affirmations.Always my best to you...
- Scott
Posted by Englishman006! on June 7, 2013, at 4:21:55
In reply to Seroquel, Metformin and Insulin Resistance, posted by andrewb on April 14, 2013, at 21:37:40
Hey Andy! I can't believe it, I was just showing my partner, some of your old posts. She is a psychologist and was telling me about her patient who had suffered greatly throughout her life, how she finally found happiness recently, only to be diagnosed with breast cancer. Life can be so cruel. I replied, remember that guy who saved my life (you) it was the same story. She knows how upset I get when I think about what happened to you. I read her one of your posts in which you said how well you were, and feeling blessed. You also enthusiastically remarked "who knows what the future might bring". As I read those words a tear rolled down my cheek.
"He finally found happiness, I said, only to fall victim to cancer".
I looked at your long list of posts intending to read her the ones which had influenced me and which had ultimately saved me. Then I see one dated April 2013...? I re-read it three times! No way I thought, it can't be? I honestly thought after our last telephone conversation when you informed of your pending bone marrow transplant, that I thought you had lost your battle. Remember I sent you that book 'The Patient From Hell'? I refrained from calling as I didn't want to upset whoever might pick up!
This has truly made my day. A fantastic surprise to know you are still with us my friend. :)))
Take care
Your grateful friend,
Shaun
Posted by Englishman006! on June 7, 2013, at 21:56:38
In reply to Re: Seroquel, Metformin and Insulin Resistance » andrewb, posted by Englishman006! on June 7, 2013, at 4:21:55
Posted by andrewb on June 19, 2013, at 13:44:42
In reply to Re: Seroquel, Metformin and Insulin Resistance » andrewb, posted by Englishman006! on June 7, 2013, at 4:21:55
Shaun,
So good to hear from you! Still have my email address? It is the same. Thanks you so much for your kind and generous thoughts.
I still have cancer, but I'm in a nice long remission and am currently enjoying excellent health (soccer and all). Funny thing, haven't had any issues with depression or used any medication for many years. I'm still gaining perspective on why I am happy and so stress free now. Needless to say, I feel blessed. But what I want to say here is that cancer (or any serious health condition) does not mean the end to happiness. I base this not only on my ongoing cancer experience but also my father's and mother's. Prepare to be amazed.
Best Wishes
Andrew
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