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Seroquel, Metformin and Insulin Resistance

Posted by andrewb on April 14, 2013, at 21:37:40

In reply to Thanks Toph (nm) » Toph, posted by Phil on April 5, 2013, at 15:38:13

Good luck with the Metformin. It not only may help control your weight but also it should help prevent diabetes from developing. Seroquel elevates prolactin (via D2 antagonism) and elevated prolactin causes insulin resistance. This insulin resistance will cause weight gain and, given enough time, lead to diabetes. The ideal dose of Metformin for you may be 2000mg/day or so, in the extended release form ideally. It might cause your stomach to feel upset at first, give this time to go away. Follow up with an insulin resistance test (not a glucose tolerance test) to make sure this issue has been dealt with.


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poster:andrewb thread:1041542
URL: http://www.dr-bob.org/babble/20130408/msgs/1042181.html