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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by StellaMella on November 21, 2012, at 7:31:50
Does anyone know any information about new drugs in the pipeline? I can't believe how long it has been since anything novel came out. Where's the innovation? Isn't almost everything off-patent now? Has it really been like 20-30 years since we saw something that wasn't a "me too" drug??? So sad. If anyone knows where I can find a little info, I would be all ears.
Posted by neuroscience on November 21, 2012, at 10:12:12
In reply to New anti-anxiety meds in the pipeline?, posted by StellaMella on November 21, 2012, at 7:31:50
> Does anyone know any information about new drugs in the pipeline? I can't believe how long it has been since anything novel came out. Where's the innovation? Isn't almost everything off-patent now? Has it really been like 20-30 years since we saw something that wasn't a "me too" drug??? So sad. If anyone knows where I can find a little info, I would be all ears.
What's the newest thing for anxiety anyway? Lyrica?
Posted by Hugh on November 21, 2012, at 11:01:10
In reply to New anti-anxiety meds in the pipeline?, posted by StellaMella on November 21, 2012, at 7:31:50
This site lists drugs that are in phase II and phase III trials for anxiety, depression, bipolar, ADHD and insomnia. Most of the drugs listed are in phase II trials, so if the trials are successful, it'll be years before the drugs reach the market. Very frustrating.
Posted by StellaMella on November 21, 2012, at 11:05:57
In reply to Re: New anti-anxiety meds in the pipeline?, posted by Hugh on November 21, 2012, at 11:01:10
I've seen that before... Problem is that it hasn't been updated since 2011. Used to get updated a lot.
Posted by Phillipa on November 21, 2012, at 14:53:03
In reply to Re: New anti-anxiety meds in the pipeline? » Hugh, posted by StellaMella on November 21, 2012, at 11:05:57
Shoot there is another read about it the other day? Will look in a bit. Phillipa
Posted by rjlockhart37 on November 21, 2012, at 20:56:59
In reply to Re: New anti-anxiety meds in the pipeline? » StellaMella, posted by Phillipa on November 21, 2012, at 14:53:03
yea .... lyrica was used a psych hospital for anxiety, but they always insisted on using crapass hydroxayine
definetly GABA meds like depakote, gabitril, ones that have indirect methods instead of the full GABA by benzos. I don't know....that's just a guess....gaba transmission is good for anxiety.
Posted by jono_in_adelaide on November 22, 2012, at 0:02:18
In reply to Re: New anti-anxiety meds in the pipeline?, posted by rjlockhart37 on November 21, 2012, at 20:56:59
Anxiolytics are so 1970's, antidepressants and atypical antipsychotics are where the money is these days!
Posted by ChicagoKat on November 28, 2012, at 12:50:09
In reply to Re: New anti-anxiety meds in the pipeline?, posted by Hugh on November 21, 2012, at 11:01:10
> This site lists drugs that are in phase II and phase III trials for anxiety, depression, bipolar, ADHD and insomnia. Most of the drugs listed are in phase II trials, so if the trials are successful, it'll be years before the drugs reach the market. Very frustrating.
>
> http://www.neurotransmitter.net/newdrugs.htmlI WANT TO BE IN A COMA UNTIL NEW DRUGS COME OUT. Awesome link Hugh, thank you. It's def on my favorites list now. I'm especially interested in the Tyrima, a reversible MAO-A inhibitor? Yes, please.
But I bet out of that long list, about 2 or 3 of the drugs max actually become available. Still, it's great to see they are trying to develop new agents.
Kat
Posted by ChicagoKat on November 28, 2012, at 12:52:06
In reply to Re: New anti-anxiety meds in the pipeline?, posted by rjlockhart37 on November 21, 2012, at 20:56:59
> yea .... lyrica was used a psych hospital for anxiety, but they always insisted on using crapass hydroxayine
>
> definetly GABA meds like depakote, gabitril, ones that have indirect methods instead of the full GABA by benzos. I don't know....that's just a guess....gaba transmission is good for anxiety.
>I personally have a love affair going on with GABA. Problem is my love is pretty much unrequited.
Kat
>
Posted by ChicagoKat on November 28, 2012, at 13:03:04
In reply to Re: New anti-anxiety meds in the pipeline?, posted by jono_in_adelaide on November 22, 2012, at 0:02:18
> Anxiolytics are so 1970's, antidepressants and atypical antipsychotics are where the money is these days!
But we need new anxiolytics!!!!! We should form a group and protest at the drug comapnies about it.
I am tolerant to benzos, tolerant to gabapentin, Lyrica makes me crazy, antihistamines give me paradoxical agitation, Remeron paradoxically makes me agitated now too, I get akathisia with any antipsychotic, and even my friend Nardil has turned on me and does nothing for my anxiety anymore.
Oh, if only benzos still worked for me. Well they would, but I'd have to take half the bottle to get an effect. They blissfully reduce your anxiety when you first try them. I'm agnostic, and I hope I don't offend anyone, but if there is a god, it seems like he or she is messing with us...every rose has thorns, every kitten has claws, and every benzo is absolutely wonderful but then the tolerance and addiction step in.
Kat
Posted by Phillipa on November 28, 2012, at 20:54:29
In reply to Re: New anti-anxiety meds in the pipeline? » jono_in_adelaide, posted by ChicagoKat on November 28, 2012, at 13:03:04
Kat said perfectly. Same here with benzos. Phillipa
This is the end of the thread.
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