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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 13 of 13. This is the beginning of the thread.
Posted by novelagent on June 15, 2012, at 9:35:28
This one focises on residual cognitive impairment following a history of amphetamine abuse. Substantial change was noticed, including improvement in academic functioning and cognitive tests after three months. I should note it takes a solid three month investment beforeo one can begin to notice improvement, but it's huge once it happens...
Posted by rjlockhart04-08 on June 15, 2012, at 15:34:02
In reply to another study on Aricept for amphetamine addiction, posted by novelagent on June 15, 2012, at 9:35:28
my addiction psychiatrist was going to use this....and then lousely said she could not do it because the prozac I take....and just sat their and said "i can't do anything, sorry" ugh!! i hate these doctors that leave a open situation of need and neglect. These are the real quacks, and I cannot stand these doctors at all, it's good to start insulting them and ask them how much nothinginness are they going to provide, waste money and time while they sit their in the self rightous delusion of being right and doing nothing....
anyways, aricept restores parts of the brain that are lost due to rapid and frequent use of AMP, also another good one is Nemanda.
rj
Posted by Phillipa on June 15, 2012, at 16:29:19
In reply to Re: another study on Aricept for amphetamine addiction, posted by rjlockhart04-08 on June 15, 2012, at 15:34:02
Aricept makes sense as original purpose Alzheimers. Good luck. Phillipa
Posted by novelagent on June 15, 2012, at 17:03:55
In reply to Re: another study on Aricept for amphetamine addiction, posted by rjlockhart04-08 on June 15, 2012, at 15:34:02
So why don't you offer to go off the Prozac? Antidepressants don't actually do anything, and the Aricept boosts mood so much, you won't miss it.
It sounds like your doc knows what's she's doing, aside from being off about the Prozac and Aricept (I took lexapro with aricept, so I know she doesn't know what she's talking about with that). You should stick with your doc, and work with her.
> my addiction psychiatrist was going to use this....and then lousely said she could not do it because the prozac I take....and just sat their and said "i can't do anything, sorry" ugh!! i hate these doctors that leave a open situation of need and neglect. These are the real quacks, and I cannot stand these doctors at all, it's good to start insulting them and ask them how much nothinginness are they going to provide, waste money and time while they sit their in the self rightous delusion of being right and doing nothing....
>
> anyways, aricept restores parts of the brain that are lost due to rapid and frequent use of AMP, also another good one is Nemanda.
>
> rj
Posted by g_g_g_unit on June 16, 2012, at 0:39:40
In reply to Re: another study on Aricept for amphetamine addiction » rjlockhart04-08, posted by novelagent on June 15, 2012, at 17:03:55
>Antidepressants don't actually do anything, and the >Aricept boosts mood so much, you won't miss it.
>Maybe you were being deliberately provocative, but this obviously isn't true. They may do little, in terms of mood, for mild-moderate depression, but when I was bedridden with leaden paralysis, Lexapro, at the very least, got me able to walk and move and function again.
Anyway, do you think Acetylcholinesterase inhibitors would be bad for OCD? I also have ADHD, and depression-related cognitive impairments, so am intrigued by Aricept.
Posted by SLS on June 17, 2012, at 6:51:18
In reply to Re: another study on Aricept for amphetamine addiction » rjlockhart04-08, posted by novelagent on June 15, 2012, at 17:03:55
> Antidepressants don't actually do anything, and the Aricept boosts mood so much, you won't miss it.
I imagine this is true for you.
- Scott
Posted by novelagent on June 17, 2012, at 22:30:54
In reply to Re: another study on Aricept for amphetamine addiction » novelagent, posted by g_g_g_unit on June 16, 2012, at 0:39:40
As with any dopamine increasernegic (not a real world), it's possible it could cause hypersexuality, or make you want to gamble, or something like that, but it's reversible, so you can just stop it if that happens. Good luck =)
It's been studied a lot for ADHD. with mixed results. But it can't hurt.
> >Antidepressants don't actually do anything, and the >Aricept boosts mood so much, you won't miss it.
> >
>
> Maybe you were being deliberately provocative, but this obviously isn't true. They may do little, in terms of mood, for mild-moderate depression, but when I was bedridden with leaden paralysis, Lexapro, at the very least, got me able to walk and move and function again.
>
> Anyway, do you think Acetylcholinesterase inhibitors would be bad for OCD? I also have ADHD, and depression-related cognitive impairments, so am intrigued by Aricept.
Posted by SLS on June 17, 2012, at 23:55:39
In reply to Re: another study on Aricept for amphetamine addiction » novelagent, posted by g_g_g_unit on June 16, 2012, at 0:39:40
> Anyway, do you think Acetylcholinesterase inhibitors would be bad for OCD? I also have ADHD, and depression-related cognitive impairments, so am intrigued by Aricept.
What do you find intriguing about Aricept?
- Scott
Posted by g_g_g_unit on June 18, 2012, at 3:20:43
In reply to Re: another study on Aricept for amphetamine addiction » g_g_g_unit, posted by SLS on June 17, 2012, at 23:55:39
> > Anyway, do you think Acetylcholinesterase inhibitors would be bad for OCD? I also have ADHD, and depression-related cognitive impairments, so am intrigued by Aricept.
>
> What do you find intriguing about Aricept?
>
>
> - ScottOh, I suppose I find the idea of anything that might improve cognition (not to mention boost mood) intriguing, since I function at quite a pitiful level (given my euthmymic IQ and all).
Stimulants are somewhat useful in this regard, but they make me more robotic and alter my interests, i.e. I can't enjoy stuff like fiction, movies etc. as readily.
I also don't find they enhance creative free-thinking or introspection much.
I was just interested in how acetylcholinesterase inhibitors might effect me. I e-mailed Dr. Jenike (Harvard's OCD psychiatrist) and he said he's never seen a negative correlation between acetylcholinesterase increases and OCD, pointing towards Memantine.
I didn't want to bug him further, but isn't hitting the Nicotinic Acetylcholine receptor going to have different effects to the Muscarinic receptor?
Also, what's the relationship between straight-up Choline and Acetylcholine? Are they different entities, with different effects?
Posted by novelagent on June 18, 2012, at 23:26:52
In reply to Re: another study on Aricept for amphetamine addiction » SLS, posted by g_g_g_unit on June 18, 2012, at 3:20:43
If you do take aricept, take it with 500mg each morning of CDP Choline (aka citicoline). Jarrow's is good.
There's been s study of galantamine and CDP Choline for schizophrenia (cognitive impairment). It has good theory behind it. CDP choline is synthetic, and passes the blood brain barrier (as opposed to choline bitarate) to convert to choline. This becomes synergystic with an anticholinterase drug like galantamine or aricept.
> > > Anyway, do you think Acetylcholinesterase inhibitors would be bad for OCD? I also have ADHD, and depression-related cognitive impairments, so am intrigued by Aricept.
> >
> > What do you find intriguing about Aricept?
> >
> >
> > - Scott
>
> Oh, I suppose I find the idea of anything that might improve cognition (not to mention boost mood) intriguing, since I function at quite a pitiful level (given my euthmymic IQ and all).
>
> Stimulants are somewhat useful in this regard, but they make me more robotic and alter my interests, i.e. I can't enjoy stuff like fiction, movies etc. as readily.
>
> I also don't find they enhance creative free-thinking or introspection much.
>
> I was just interested in how acetylcholinesterase inhibitors might effect me. I e-mailed Dr. Jenike (Harvard's OCD psychiatrist) and he said he's never seen a negative correlation between acetylcholinesterase increases and OCD, pointing towards Memantine.
>
> I didn't want to bug him further, but isn't hitting the Nicotinic Acetylcholine receptor going to have different effects to the Muscarinic receptor?
>
> Also, what's the relationship between straight-up Choline and Acetylcholine? Are they different entities, with different effects?
Posted by 3 Beer Effect on June 20, 2012, at 6:36:46
In reply to another study on Aricept for amphetamine addiction, posted by novelagent on June 15, 2012, at 9:35:28
DMAE helps increase acetylcholine & is OTC. It is pretty strong at 100 mg. I recommend the Twinlab brand. It takes about 3 weeks to really start working. One side effect - you will begin to remember every bad thing you have ever done, even stuff you had forgotten from years ago - which helps to prevent relapse.
Posted by g_g_g_unit on June 21, 2012, at 4:27:27
In reply to Re: another study on Aricept for amphetamine addiction » g_g_g_unit, posted by novelagent on June 18, 2012, at 23:26:52
> If you do take aricept, take it with 500mg each morning of CDP Choline (aka citicoline). Jarrow's is good.
So is Choline a precursor to Acetylcholine? In other words, 5-htp:Serotonin::Choline:Acetylcholine?
There are quite a few anecdotal reports of supplemental choline worsening OCD. This study links "medical thalamic Choline" (whatever that means) to pediatric OCD: http://www.ncbi.nlm.nih.gov/pubmed/14675804
That said, I find Nicotine administration has highly beneficial effects on my OCD symptoms. I guess the only way to find out re: ACh-inhibitors would be to experiment.
Posted by rjlockhart04-08 on June 21, 2012, at 22:47:32
In reply to DMAE helps too, posted by 3 Beer Effect on June 20, 2012, at 6:36:46
I have to say I have read alot of your posts from the past before I started posting here...vary good info on what I have questions on and no one knew a flutz what I was talking about....
seriously I am so glad to see you back!
rj
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