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Re: another study on Aricept for amphetamine addiction » SLS

Posted by g_g_g_unit on June 18, 2012, at 3:20:43

In reply to Re: another study on Aricept for amphetamine addiction » g_g_g_unit, posted by SLS on June 17, 2012, at 23:55:39

> > Anyway, do you think Acetylcholinesterase inhibitors would be bad for OCD? I also have ADHD, and depression-related cognitive impairments, so am intrigued by Aricept.
>
> What do you find intriguing about Aricept?
>
>
> - Scott

Oh, I suppose I find the idea of anything that might improve cognition (not to mention boost mood) intriguing, since I function at quite a pitiful level (given my euthmymic IQ and all).

Stimulants are somewhat useful in this regard, but they make me more robotic and alter my interests, i.e. I can't enjoy stuff like fiction, movies etc. as readily.

I also don't find they enhance creative free-thinking or introspection much.

I was just interested in how acetylcholinesterase inhibitors might effect me. I e-mailed Dr. Jenike (Harvard's OCD psychiatrist) and he said he's never seen a negative correlation between acetylcholinesterase increases and OCD, pointing towards Memantine.

I didn't want to bug him further, but isn't hitting the Nicotinic Acetylcholine receptor going to have different effects to the Muscarinic receptor?

Also, what's the relationship between straight-up Choline and Acetylcholine? Are they different entities, with different effects?

 

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