![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by Terry8 on March 16, 2011, at 15:08:52
I didn't see anything in the archives, but my apologies if this has been discussed before. I'm newish to Parnate and experiencing the usual nighttime insomnia and afternoon fatigue. I've heard that you should take the doses earlier in the day to prevent insomnia, but most people seem to have the problem anyway. What about flip flopping the timing entirely?
I take my doses at 8am, 12pm, and 3pm. By 2pm I'm very tired, and though I haven't been napping in the afternoon, I'm sure if I let myself I could fall asleep in a heartbeat. But by 8pm I'm wide awake again and can't get to sleep until 2am at the earliest. So I get really tired six hours after the first dose, and am wide awake another six hours later.
What if I were to take the doses in the evening, starting around dinnertime? So a first dose at 6pm, a second at 9pm, and last one at midnight (followed by going to bed). If the pattern holds, I'd be tired and ready to sleep six hours after the first dose (around midnight) and waking up again six hours later, around 6am -- a bit more like the rest of the world.
Or does it not work like that? Has anybody tried this?
Thanks!
Posted by linkadge on March 16, 2011, at 15:22:49
In reply to Nighttime Parnate dosing?, posted by Terry8 on March 16, 2011, at 15:08:52
Its very common in MAO users to have the pattern of midday fatigue and late nate partial insomnia. Mice lacking MAO, show the exact same pattern of sleep/wake.
Anyhow, since the MAO action takes a while to react stedy state (and to return to normal) you'd think it wouldn't matter.
Parante might be a little different in that it does have some stimulant like activity. I would avoid it in the late evening. But, if parnate is not stimulating for you, you could always try it in the evening. But, I think a lot of MAO users fall into the pattern of dual sleep cycles.
Linkadge
Posted by Terry8 on March 18, 2011, at 8:27:49
In reply to Re: Nighttime Parnate dosing?, posted by linkadge on March 16, 2011, at 15:22:49
> Its very common in MAO users to have the pattern of midday fatigue and late nate partial insomnia. Mice lacking MAO, show the exact same pattern of sleep/wake.
>
> Anyhow, since the MAO action takes a while to react stedy state (and to return to normal) you'd think it wouldn't matter.
>
> Parante might be a little different in that it does have some stimulant like activity. I would avoid it in the late evening. But, if parnate is not stimulating for you, you could always try it in the evening. But, I think a lot of MAO users fall into the pattern of dual sleep cycles.
>
> Linkadge>Thanks for your reply. I wasn't sure whether it was the MAO inhibition causing the insomnia/daytime fatigue, or something related to the immediate action of each dose. I know Parnate is famous for causing insomnia, but I didn't know whether other MAOIs like Nardil would have the same effect, or if it was just related to Parnate being especially activating. Maybe I'll just accept the new cycle and embrace a midday nap...
Posted by Elanor Roosevelt on March 22, 2011, at 23:23:05
In reply to Nighttime Parnate dosing?, posted by Terry8 on March 16, 2011, at 15:08:52
If you are tired by 2 why don't you shift all of your doses, get a later start and let your last dose be at 5
Posted by Terry8 on March 24, 2011, at 15:03:42
In reply to Re: Nighttime Parnate dosing?, posted by Elanor Roosevelt on March 22, 2011, at 23:23:05
> If you are tired by 2 why don't you shift all of your doses, get a later start and let your last dose be at 5
Hm, so take doses at, say, 11am, 2pm, and 5pm? That could be worth it if it pushes the drowsiness into the evening; I'd just be worried about sleeping through the night with the last dose so late. But it's thought to try. Thanks.
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.