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Dr. Bob is Robert Hsiung, MD,
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Posted by linkadge on August 29, 2010, at 21:01:59
Agents which act as both trk-b agonistand sigma-1r agonists would exhibit potent neurotrophic activity.
Fluvoxamine is a sigma agonist but not a trk-b agonist. Amitriptyline is a potent trk-b agonist but has lesser effect on sigma receptors.
what about combining fluvoxamine and amitriptyline? This would theoretically be potently neurotrophic.
Linkadge
Posted by Dr. Bob on August 30, 2010, at 0:50:27
In reply to Trk-b sigma-1r, posted by linkadge on August 29, 2010, at 21:01:59
> Agents which act as both trk-b agonistand sigma-1r agonists would exhibit potent neurotrophic activity.
Sorry to interrupt, but I'd like to redirect this thread to Psycho-Babble Neurotransmitters. Here's a link:
http://www.dr-bob.org/babble/neuro/20100607/msgs/960610.html
Please do feel free to continue this discussion there, and in general to check out the other boards here.
That will be considered a new thread, so if you'd like to receive notifications by email of follow-ups to it, you'll need to request that there. Thanks,
Bob
This is the end of the thread.
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